Clement MK, Pimentel CS, Swaine JA, Pimentel AJ, Hutchins D, McGaughy JA (2019) Dissociable attentional effects of dopaminergic and cholinergic lesions to the anterior cingulate cortex. Neuroscience 2019 Abstracts 418.11. Society for Neuroscience, Chicago, IL. Summary: Prior work from our lab has shown that excitotoxic lesions to the anterior cingulate cortex (ACC) impairs the ability […]
Kruashvili L, Beselia G, Chkhikvishvili N (2019) Effect of medial septal selective and non selective lesions on exploratory behavior and recognition memory. Neuroscience 2019 Abstracts 336.01. Society for Neuroscience, Chicago, IL. Summary: Investigation of cholinergic system and memory interaction has especially become the object of scientific attention due to the clinical and experimental data, in
Bhyrapuneni G, Benade V, Daripelli S, Kamuju V, Shinde A, Abraham R, Nirogi R, Jasti V (2019) SUVN-G3031, histamine H3 receptor inverse agonist preclinical evaluation for the treatment of excessive daytime sleepiness in narcolepsy. Neuroscience 2019 Abstracts 502.07. Society for Neuroscience, Chicago, IL. Summary: Numerous studies have demonstrated that brain histamine plays a crucial role
Harris RB (2019) Leptin receptor activity in the nucleus of the solitary tract increases forebrain leptin sensitivity. Neuroscience 2019 Abstracts 591.04. Society for Neuroscience, Chicago, IL. Summary: We previously reported that fourth ventricle infusions of leptin that cause weight loss are associated with an increase in hypothalamic phosphorylation of signal transducer and activator of transcription
Galvan MA, Shramm PA, Bouajram R, Lappi DA, Ancheta LR (2019) A high efficacy selection method for transfected cells utilizing recombinant isolectin B4-saporin. Neuroscience 2019 Abstracts 794.10. Society for Neuroscience, Chicago, IL. Summary: Transfection protocols often rely on the use of antibiotics for the selection of transfected cells and has become the accepted approach for
Suarez AN, Liu CM, Cortella AM, Noble EN, Kanoski SE (2019) Medial septum cholinergic signaling regulates gastrointestinal-derived vagus sensory nerve communication to the hippocampus. Neuroscience 2019 Abstracts 601.19. Society for Neuroscience, Chicago, IL. Summary: The vagus nerve delivers bi-directional communication between feeding-relevant gastrointestinal (GI) signals and the brain. Vagal sensory-mediated GI satiation signals, including gastric
Cunningham C, Lowry JP (2019) In vivo monitoring of cholinergic neurotransmission with a microelectrochemical choline biosensor. Neuroscience 2019 Abstracts 614.03. Society for Neuroscience, Chicago, IL. Summary: Acetylcholine acts as a key neuromodulator within the central nervous system, capable of altering neuronal excitability and coordinating neuronal firing patterns. Conversely, cholinergic neurotransmission plays a crucial role in
Walker JR, Ong A, Detloff MR (2019) Role of nociceptive afferent input on forelimb reaching and grasping behaviors in the spinal cord injured rat. Neuroscience 2019 Abstracts 572.09. Society for Neuroscience, Chicago, IL. Summary: Individuals with spinal cord injury (SCI) suffer a loss of motor and sensory function. The current standard of care to recover
Grayson VS, Han Y, Guedea AL, Jovasevic V, Gao C, Apkarian A, Radulovic JM (2019) The role of subcortical hippocampal inputs in contextual memory formation. Neuroscience 2019 Abstracts 786.03. Society for Neuroscience, Chicago, IL. Summary: The role of cortical efferents to the hippocampus in the formation of episodic-like memory is well established, however, less is
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Osterlund JR, BLackwell AA, Lipton M, Castillo V, Kartje GL, Tsai S-Y, Wallace DG (2019) Selective loss of septohippocampal cholinergic projections is associated with more circuitous homeward progressions. Neuroscience 2019 Abstracts 789.11. Society for Neuroscience, Chicago, IL. Summary: Rodents rely on self-movement cues as a source of information to maintain spatial orientation during exploration. The