Author name: Kristen Hartman

Lack of effect of intraventricular OX7-saporin on working memory in the rat.

Wrenn CC, Lappi DA, Wiley RG (1999) Lack of effect of intraventricular OX7-saporin on working memory in the rat. Neuroscience 1999 Abstracts 559.5. Society for Neuroscience, Miami, FL. Summary: The immunotoxin 192 IgG-saporin (192-sap) has been shown by our laboratory and others to be a highly selective agent for the production of lesions of the […]

Lack of effect of intraventricular OX7-saporin on working memory in the rat. Read More »

A developmental role of the cholinergic basal forebrain: behavioural and neurochemical effects of neonatal 192 IgG-saporin lesions.

Ricceri L, Calamandrei G, Berger-Sweeney J (1999) A developmental role of the cholinergic basal forebrain: behavioural and neurochemical effects of neonatal 192 IgG-saporin lesions. Neuroscience 1999 Abstracts 559.6. Society for Neuroscience, Miami, FL. Summary: Cholinergic basal forebrain (BF) fibers begin to innervate neocortex and hippocampus during the first week of life in rodents. Because this

A developmental role of the cholinergic basal forebrain: behavioural and neurochemical effects of neonatal 192 IgG-saporin lesions. Read More »

GABAergic septohippocampal neurons are not necessary for spatial memory. (Poster)

Secor A, Nocera R, Pang KCH (1999) GABAergic septohippocampal neurons are not necessary for spatial memory. (Poster). Neuroscience 1999 Abstracts 559.9 . Society for Neuroscience, Miami, FL. Summary: The medial septum/diagonal band of Broca (MS-DB) provides a major input to the hippocampus, and nonselective lesions of MS-DB neurons or their projections to the hippocampus impair

GABAergic septohippocampal neurons are not necessary for spatial memory. (Poster) Read More »

Selective immunolesion of substance P receptor expressing interneurons in the hippocampus.

Borhegyi ZS, Wiley RG, Lappi DA, Morrell J, Buzsáki G (1999) Selective immunolesion of substance P receptor expressing interneurons in the hippocampus. Neuroscience 1999 Abstracts 561.15. Society for Neuroscience, Miami, FL. Summary: A ribosome inactivating protein, saporin, conjugated to substance P (SP-SAP) was used to selectively damage substance P receptor expressing interneurons in the dentate

Selective immunolesion of substance P receptor expressing interneurons in the hippocampus. Read More »

Inhibition of mustard oil-induced thermal hyperalgesia in an operant escape task by substance P-saporin.

Wiley RG, Lappi DA, Vierck CJ (1999) Inhibition of mustard oil-induced thermal hyperalgesia in an operant escape task by substance P-saporin. Neuroscience 1999 Abstracts 271.1. Society for Neuroscience, Miami, FL. Summary: Substance P (SP) armed with the ribosome inactivating protein, saporin (SAP), selectively destroys neurons expressing the NK-1 receptor, attenuates withdrawal responses after capsaicin injection,

Inhibition of mustard oil-induced thermal hyperalgesia in an operant escape task by substance P-saporin. Read More »

Depletion of IB4-binding sensory neurons results in elevated nociceptive thresholds.

Vulchanova L, Stone LS, Olson T, Riedl MS, Elde R, Honda CN (1999) Depletion of IB4-binding sensory neurons results in elevated nociceptive thresholds. Neuroscience 1999 Abstracts 272.8. Society for Neuroscience, Miami, FL. Summary: The lectin IB4 binds to and is specifically taken up by a subset of small sensory neurons, proposed to play a role

Depletion of IB4-binding sensory neurons results in elevated nociceptive thresholds. Read More »

NGF-mediated alteration of NF-κB binding activity after partial immuno-lesions to rat cholinergic basal forebrain neurons.

Gu Z, Toliver-Kinsky T, Glasgow J, Cain L, Perez-Polo JR (1999) NGF-mediated alteration of NF-κB binding activity after partial immuno-lesions to rat cholinergic basal forebrain neurons. Neuroscience 1999 Abstracts 300.15. Society for Neuroscience, Miami, FL. Summary: Memory loss and cognitive deficits in die aged and in patients with Alzheimer’s disease (AD) are often associated with

NGF-mediated alteration of NF-κB binding activity after partial immuno-lesions to rat cholinergic basal forebrain neurons. Read More »

Lesions of basal forebrain cholinergic neurons eliminate the modulatory effects of benzodiazepine receptor ligands on behavioral and cardiovascular reactions in an anxiogenic paradigm.

Stowell JR, Bemtson GG, Sarter M (1999) Lesions of basal forebrain cholinergic neurons eliminate the modulatory effects of benzodiazepine receptor ligands on behavioral and cardiovascular reactions in an anxiogenic paradigm. Neuroscience 1999 Abstracts 358.5. Society for Neuroscience, Miami, FL. Summary: We have previously shown that basal forebrain cortical cholinergic projections mediate potentiation of the cardiovascular

Lesions of basal forebrain cholinergic neurons eliminate the modulatory effects of benzodiazepine receptor ligands on behavioral and cardiovascular reactions in an anxiogenic paradigm. Read More »

Exciting New Advances in Pain Research and Treatment Using Receptor Internalization Technologies – SFN 1999 Symposium

Symposium:  “Exciting New Advances in Pain Research and Treatment Using Receptor Internalization Technologies” Society for Neuroscience (SFN) Symposium October 23-28, 1999 – Miami, Florida D.A. Thomas, NIDA-NIH (co-chair); R.G. Wiley, Vanderbilt University; W.J. Martin, UCSF; M.J. Iadorola, NIDCR-NIH; P. Mantyh, University of Minnesota; R.M. Caudle, University of Florida (co-chair)  A press conference was held prior

Exciting New Advances in Pain Research and Treatment Using Receptor Internalization Technologies – SFN 1999 Symposium Read More »

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