Author name: Kristen Hartman

Expert Opinion: Managing sleep disturbances in people with epilepsy

Nobili L, Beniczky S, Eriksson SH, Romigi A, Ryvlin P, Toledo M, Rosenzweig I (2021) Expert Opinion: Managing sleep disturbances in people with epilepsy. Epilepsy Behav 124:108341. doi: 10.1016/j.yebeh.2021.108341 Summary: The authors suggest that the dose and timing of antiepileptic medications and other co-medications should always be optimized in order to improve nocturnal sleep and […]

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Heart failure impairs mood and memory in male rats and down-regulates the expression of numerous genes important for synaptic plasticity in related brain regions

Parent MB, Ferreira-Neto HC, Kruemmel AR, Althammer F, Patel AA, Keo S, Whitley KE, Cox DN, Stern JE (2021) Heart failure impairs mood and memory in male rats and down-regulates the expression of numerous genes important for synaptic plasticity in related brain regions. Behav Brain Res 414:113452. doi: 10.1016/j.bbr.2021.113452 Objective: To assess the effects of

Heart failure impairs mood and memory in male rats and down-regulates the expression of numerous genes important for synaptic plasticity in related brain regions Read More »

Toll-like receptor 4-mediated enteric glia loss is critical for the development of necrotizing enterocolitis

Kovler ML, Gonzalez Salazar AJ, Fulton WB, Lu P, Yamaguchi Y, Zhou Q, Sampah M, Ishiyama A, Prindle T Jr, Wang S, Jia H, Wipf P, Sodhi CP, Hackam DJ (2021) Toll-like receptor 4-mediated enteric glia loss is critical for the development of necrotizing enterocolitis. Sci Transl Med 13(612):eabg3459. doi: 10.1126/scitranslmed.abg3459 PMID: 34550727 Objective: Hypothesized

Toll-like receptor 4-mediated enteric glia loss is critical for the development of necrotizing enterocolitis Read More »

Overexpression of nerve growth factor in the hippocampus induces behavioral changes in rats with 192IgG-saporin-induced cholinergic deficit

Dobryakova YV, Zaichenko MI, Spivak YS, Stepanichev MY, Markevich VA, Bolshakov AP (2021) Overexpression of nerve growth factor in the hippocampus induces behavioral changes in rats with 192IgG-saporin-induced cholinergic deficit. Neurochem J 15:273-281. doi: 10.1134/S1819712421030028 Summary: Degeneration of septal cholinergic neurons caused by the immunotoxin 192-IgG-SAP produces a model of the pathological state that occurs

Overexpression of nerve growth factor in the hippocampus induces behavioral changes in rats with 192IgG-saporin-induced cholinergic deficit Read More »

The protective effects of AT2R agonist, CGP42112A, against angiotensin ii-induced oxidative stress and inflammatory response in astrocytes: role of AT2R/PP2A/NFκB/ROS signaling

Bhat SA, Fatima Z, Sood A, Shukla R, Hanif K (2021) The protective effects of AT2R agonist, CGP42112A, against angiotensin ii-induced oxidative stress and inflammatory response in astrocytes: role of AT2R/PP2A/NFκB/ROS signaling. Neurotox Res 39(6):1991-2006. doi: 10.1007/s12640-021-00403-4 PMID: 34529240 Objective: To evaluate the role and molecular mechanism of AT2R agonist CGP against Angiotensin II-induced astrocytic

The protective effects of AT2R agonist, CGP42112A, against angiotensin ii-induced oxidative stress and inflammatory response in astrocytes: role of AT2R/PP2A/NFκB/ROS signaling Read More »

Dorso-ventral heterogeneity in tracheal basal stem cells

Tadokoro T, Tanaka K, Osakabe S, Kato M, Kobayashi H, Hogan BLM, Taniguchi H (2021) Dorso-ventral heterogeneity in tracheal basal stem cells. Biol Open 10(9):bio058676. doi: 10.1242/bio.058676 PMID: 34396394 Objective: To determine whether tracheal basal cells (BCs) from the dorso-ventral airways have intrinsic molecular and behavioural differences relevant to their in vivo function. Summary: This

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The biology of hematopoietic stem cells and its clinical implications

Skulimowska I, Sosniak J, Gonka M, Szade A, Jozkowicz A, Szade K (2021) The biology of hematopoietic stem cells and its clinical implications. FEBS J 16192. doi: 10.1111/febs.16192 Objective: To review the opportunities and challenges of recent findings to improve the clinical use of hematopoietic stem cells (HSCs) Summary: The authors describe new methods of

The biology of hematopoietic stem cells and its clinical implications Read More »

Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats

Duggan MR, Joshi S, Strupp J, Parikh V (2021) Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats. Brain Struct Funct 226(7):2357-2373. doi: 10.1007/s00429-021-02336-2 Objective: To test the hypothesis that reduced PFC output would exert differential effects on attentional capacities in young and aged rats, with the

Chemogenetic inhibition of prefrontal projection neurons constrains top-down control of attention in young but not aged rats Read More »

Neural circuitry underlying REM sleep: A review of the literature and current concepts

Wang YQ, Liu WY, Li L, Qu WM, Huang ZL (2021) Neural circuitry underlying REM sleep: A review of the literature and current concepts. Prog Neurobiol 204:102106. doi: 10.1016/j.pneurobio.2021.102106 Summary: To investigate the role of the LC in sleep the authors injected 0.3 µl of 192-Saporin (Cat. IT-01) or anti-DBH-SAP (Cat. #IT-03) at 1 µg/µl.

Neural circuitry underlying REM sleep: A review of the literature and current concepts Read More »

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