Author name: Kristen Hartman

Neuropeptide-toxin conjugates in pain research and treatment. (Review)

Wiley RG (2000) Neuropeptide-toxin conjugates in pain research and treatment. (Review). Reg Anesth Pain Med 25(5):546-548. doi: 10.1053/rapm.2000.8457 Summary: Several lines of evidence indicate dorsal horn neurons that respond to substance P (SP) play a role in nociception. Wiley discusses the attributes of SP-SAP (Cat. #IT-07), a targeted toxin that eliminates cells expressing the neurokinin-1 […]

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Expression and channel properties of alpha-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons.

McNerney ME, Pardi D, Pugh PC, Nai Q, Margiotta JF (2000) Expression and channel properties of alpha-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons. J Neurophysiol 84(3):1314-1329. doi: 10.1152/jn.2000.84.3.1314 PMID: 10980005 Related Products: Nicotinic Acetylcholine Receptor alpha 1 (mAb 35) Rat Monoclonal (Cat. #AB-N36)

Expression and channel properties of alpha-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons. Read More »

Early migratory rat neural crest cells express functional gap junctions: Evidence that neural crest cell survival requires gap junction function.

Bannerman P, Nichols W, Puhalla S, Oliver T, Berman M, Pleasure D (2000) Early migratory rat neural crest cells express functional gap junctions: Evidence that neural crest cell survival requires gap junction function. J Neurosci Res 61:605-615. doi: 10.1002/1097-4547(20000915)61:63.0.CO;2-U PMID: 10972957 Summary: Gap junctions are vital for intercellular communication, especially during development. Neural crest cells

Early migratory rat neural crest cells express functional gap junctions: Evidence that neural crest cell survival requires gap junction function. Read More »

Identification of a human olfactory ensheathing cell that can effect transplant mediated remyelination of demyelinated CNS axons.

Barnett SC, Alexander CL Iwashita Y, Gilson JM, Crowther J, Clark L, Dunn KT, Papanastassiou V, Kennedy PG, Franklin RJ (2000) Identification of a human olfactory ensheathing cell that can effect transplant mediated remyelination of demyelinated CNS axons. Brain 123:1581-1588. doi: 10.1093/brain/123.8.1581 PMID: 10908188 Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)

Identification of a human olfactory ensheathing cell that can effect transplant mediated remyelination of demyelinated CNS axons. Read More »

Sympathetic reflexes after depletion of bulbospinal catecholaminergic neurons with anti-DBH-saporin.

Schreihofer AM, Guyenet PG (2000) Sympathetic reflexes after depletion of bulbospinal catecholaminergic neurons with anti-DBH-saporin. Am J Physiol Regul Integr Comp Physiol 279:R729-R742. doi: 10.1152/ajpregu.2000.279.2.R729 Related Products: Anti-DBH-SAP (Cat. #IT-03) Read the featured article in Targeting Trends.

Sympathetic reflexes after depletion of bulbospinal catecholaminergic neurons with anti-DBH-saporin. Read More »

Effects of cholinergic depletion on neural activity in different laminae of the rat barrel cortex.

Herron P, Schweitzer JB (2000) Effects of cholinergic depletion on neural activity in different laminae of the rat barrel cortex. Brain Res 872:71-76. doi: 10.1016/s0006-8993(00)02454-9 Summary: 192-SAP (Cat. #IT-01) 8.0 µg/300 g body weight, nucleus basalis of Meynert Related Products: 192-IgG-SAP (Cat. #IT-01)

Effects of cholinergic depletion on neural activity in different laminae of the rat barrel cortex. Read More »

Antibody for human p75 LNTR identifies cholinergic basal forebrain of non-primate species.

Tremere LA, Pinaud R, Grosche J, Hartig W, Rasmusson DD (2000) Antibody for human p75 LNTR identifies cholinergic basal forebrain of non-primate species. NeuroReport 11(10):2177-2183. doi: 10.1097/00001756-200007140-00023 PMID: 10923666 Summary: 192-SAP (Cat. #IT-01) is a highly successful reagent for eliminating cholinergic neurons in rats. Because the targeting antibody only recognizes rat p75, it is unable

Antibody for human p75 LNTR identifies cholinergic basal forebrain of non-primate species. Read More »

Sustained visual attention performance-associated prefrontal neuronal activity: evidence for cholinergic modulation.

Gill TM, Sarter M, Givens B (2000) Sustained visual attention performance-associated prefrontal neuronal activity: evidence for cholinergic modulation. J Neurosci 20:4745-4757. doi: 10.1523/JNEUROSCI.20-12-04745.2000 Summary: Preliminary evidence suggests that demands on attention levels are associated with changes in levels of cortical acetylcholine. Gill et al. used .05 µg 192-Saporin (Cat. #IT-01) by intracortical infusion to demonstrate

Sustained visual attention performance-associated prefrontal neuronal activity: evidence for cholinergic modulation. Read More »

Ectopic noradrenergic hyperinnervation does not functionally compensate for neonatal forebrain acetylcholine lesion.

Pappas BA, Nguyen T, Brownlee B, Tanasoiu D, Fortin T, Sherren N (2000) Ectopic noradrenergic hyperinnervation does not functionally compensate for neonatal forebrain acetylcholine lesion. Brain Res 867:90-99. doi: 10.1016/s0006-8993(00)02263-0 Summary: Removal of cholinergic forebrain neurons in the neonatal rat causes an ingrowth of hippocampal material to the affected area. The behavioral effect of this

Ectopic noradrenergic hyperinnervation does not functionally compensate for neonatal forebrain acetylcholine lesion. Read More »

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