Author name: Kristen Hartman

Janni G, Lappi DA, Ohara PT, Jasmin L (1999) CTB-saporin induced demyelinating myelopathy in the rat. Neuroscience 1999 Abstracts 731.2. Society for Neuroscience, Miami, FL. Summary: In designing a rat model of demyelinating disease, we have used a newly developed neurotoxin, the B fragment of cholera toxin (CTB) linked to the potent ribosome inactivating protein […]

Waite JJ (1999) Cholinergic deafferentation of the hippocampus or cortex produces differential modulation of attentional processing. Neuroscience 1999 Abstracts 754.4. Society for Neuroscience, Miami, FL. Summary: Dissociation of attentional changes produced by lesion of the cholinergic neurons in the medial septum (MS) and nucleus basalis magnocellularis (NBM) was investigated by selective lesion with the immunotoxin

Wrenn CC, Lappi DA, Wiley RG (1999) Lack of effect of intraventricular OX7-saporin on working memory in the rat. Neuroscience 1999 Abstracts 559.5. Society for Neuroscience, Miami, FL. Summary: The immunotoxin 192 IgG-saporin (192-sap) has been shown by our laboratory and others to be a highly selective agent for the production of lesions of the

Garcia P, Linster C, Hasselmo ME, Baxter MG (1999) Selective cholinergic lesions of the horizontal limb of the diagonal band of Broca affect odor perception in rats. Neuroscience 1999 Abstracts 559.2. Society for Neuroscience, Miami, FL. Summary: We have recently shown, in behavioral experiments with rats, that perceptual similarities between aliphatic aldehydes can be at

Ricceri L, Calamandrei G, Berger-Sweeney J (1999) A developmental role of the cholinergic basal forebrain: behavioural and neurochemical effects of neonatal 192 IgG-saporin lesions. Neuroscience 1999 Abstracts 559.6. Society for Neuroscience, Miami, FL. Summary: Cholinergic basal forebrain (BF) fibers begin to innervate neocortex and hippocampus during the first week of life in rodents. Because this

Butt AE, Bowman TD, Novotnev JS, Rogers JL, Tanabi A (1999) Selective lesions of the nucleus basalis magnocellularis in rats do not affect simple association learning. Neuroscience 1999 Abstracts 559.4. Society for Neuroscience, Miami, FL. Summary: We have previously argued that damage to the cholinergic nucleus basalis magnocellularis (NBM) selectively impairs complex or configural association

Borhegyi ZS, Wiley RG, Lappi DA, Morrell J, Buzsáki G (1999) Selective immunolesion of substance P receptor expressing interneurons in the hippocampus. Neuroscience 1999 Abstracts 561.15. Society for Neuroscience, Miami, FL. Summary: A ribosome inactivating protein, saporin, conjugated to substance P (SP-SAP) was used to selectively damage substance P receptor expressing interneurons in the dentate

Secor A, Nocera R, Pang KCH (1999) GABAergic septohippocampal neurons are not necessary for spatial memory. (Poster). Neuroscience 1999 Abstracts 559.9 . Society for Neuroscience, Miami, FL. Summary: The medial septum/diagonal band of Broca (MS-DB) provides a major input to the hippocampus, and nonselective lesions of MS-DB neurons or their projections to the hippocampus impair

Sarter M, Turchi J, Gonzalez K (1999) Effects of cortical cholinergic deafferentation upon processing capacity as assessed by an olfactory span task in rats. Neuroscience 1999 Abstracts 554.6. Society for Neuroscience, Miami, FL. Summary: Cortical cholinergic deafferentation, produced by infusions of 192 IgG-saporin into the basal forebrain of rats, results in impairments of processing capacity