Author name: Kristen Hartman

Septohippocampal acetylcholine: involved in but not necessary for learning and memory?

Parent MB, Baxter MG (2004) Septohippocampal acetylcholine: involved in but not necessary for learning and memory?. Learn Mem 11:9-20. doi: 10.1101/lm.69104 Summary: In this review the authors describe some of the methods and rationale behind the investigation of hippocampal acetylcholine and its role in the support of learning and memory processes. Results produced by the […]

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Involvement of cholinergic neuronal systems in intravenous cocaine self-administration.

Smith JE, Co C, Yin X, Sizemore GM, Liguori A, Johnson WE 3rd, Martin TJ (2004) Involvement of cholinergic neuronal systems in intravenous cocaine self-administration. Neurosci Biobehav Rev 27(8):841-850. doi: 10.1016/j.neubiorev.2003.11.002 Summary: Recent studies have demonstrated that cholinergic neurons take part in the process of cocaine self-administration. In this study the authors used 0.25 µg-injections

Involvement of cholinergic neuronal systems in intravenous cocaine self-administration. Read More »

Featured Article: Cholinergic deafferentation of the entorhinal cortex impairs working memory for novel, but not familiar stimuli in a delayed non-match to sample (DNMS) task

McGaughy J (2004) Featured Article: Cholinergic deafferentation of the entorhinal cortex impairs working memory for novel, but not familiar stimuli in a delayed non-match to sample (DNMS) task. Targeting Trends 5(1) Related Products: 192-IgG-SAP (Cat. #IT-01) Read the featured article in Targeting Trends. See Also: McGaughy JA et al. Cholinergic deafferentation of the entorhinal cortex

Featured Article: Cholinergic deafferentation of the entorhinal cortex impairs working memory for novel, but not familiar stimuli in a delayed non-match to sample (DNMS) task Read More »

Cover Article: Cholinergic Deafferentation of the Entorhinal Cortex Impairs Working Memory for Novel, but not Familiar Stimuli in a Delayed Non-Match to Sample (DNMS) Task.

Contributed by ATS’s 2003 Society for Neuroscience Poster of the Year Award Winner:Dr. Jill McGaughy, Boston University, 64 Cummington St., Boston, MA 02215 Muscarinic cholinergic receptor activation in entorhinal cortex (EC) activates intrinsic depolarizing membrane currents, which cause self-sustained spiking activity in single neurons.[1] This effect may underlie delay activity and match-dependent activity changes in

Cover Article: Cholinergic Deafferentation of the Entorhinal Cortex Impairs Working Memory for Novel, but not Familiar Stimuli in a Delayed Non-Match to Sample (DNMS) Task. Read More »

Cytochrome oxidase activity in the monkey globus pallidus and subthalamic nucleus after ablation of striatal interneurons expressing substance P receptors.

Chiken S, Hatanaka N, Tokuno H (2003) Cytochrome oxidase activity in the monkey globus pallidus and subthalamic nucleus after ablation of striatal interneurons expressing substance P receptors. Neurosci Lett 353(2):103-106. doi: 10.1016/j.neulet.2003.09.026 Summary: 1-6 µl of 15-20 ng/µl SP-SAP (Cat. #IT-07) was injected into the forelimb representation of the putamen. Animals were examined for the

Cytochrome oxidase activity in the monkey globus pallidus and subthalamic nucleus after ablation of striatal interneurons expressing substance P receptors. Read More »

Testosterone manipulation protects motoneurons from dendritic atrophy after contralateral motoneuron depletion.

Fargo KN, Sengelaub DR (2004) Testosterone manipulation protects motoneurons from dendritic atrophy after contralateral motoneuron depletion. J Comp Neurol 469(1):96-106. doi: 10.1002/cne.10991 Summary: The authors wished to investigate the therapeutic effects of testosterone on motoneuron dendrites in nerve injury models. 1 µl of a 0.1% solution of CTB-SAP (Cat. #IT-14) solution was unilaterally injected into

Testosterone manipulation protects motoneurons from dendritic atrophy after contralateral motoneuron depletion. Read More »

Relationship between CSF hypocretin levels and hypocretin neuronal loss.

Gerashchenko D, Murillo-Rodriguez E, Lin L, Xu M, Hallett L, Nishino S, Mignot E, Shiromani PJ (2003) Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp Neurol 184(2):1010-1016. doi: 10.1016/S0014-4886(03)00388-1 Summary: Narcolepsy has recently been shown to be a neurodegenerative disease. Data from several different sources indicate that narcoleptics have very low levels of

Relationship between CSF hypocretin levels and hypocretin neuronal loss. Read More »

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