Author name: Kristen Hartman

Behavioural consequences of combined cholinergic lesion and chronic cerebral hypoperfusion in rats

Rennie KE, Frechette M, Pappas BA (2007) Behavioural consequences of combined cholinergic lesion and chronic cerebral hypoperfusion in rats. Neuroscience 2007 Abstracts 698.16/R26. Society for Neuroscience, San Diego, CA. Summary: Chronic cerebral hypoperfusion compromises the health of hippocampal neurons, leading to a slowly emerging loss of pyramidal cells accompanied by spatial memory impairments in rats. […]

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Progressive decrease in sleep deprivation-induced extracellular adenosine release and recovery NREM sleep following intracerebroventricular injection of 192 IgG-saporin

Kalinchuk AV, Porkka-Heiskanen T, McCarley RW, Basheer R (2007) Progressive decrease in sleep deprivation-induced extracellular adenosine release and recovery NREM sleep following intracerebroventricular injection of 192 IgG-saporin. Neuroscience 2007 Abstracts 735.10/TT29. Society for Neuroscience, San Diego, CA. Summary: The basal forebrain (BF) is an important site in the homeostatic regulation of sleep mediated by adenosine

Progressive decrease in sleep deprivation-induced extracellular adenosine release and recovery NREM sleep following intracerebroventricular injection of 192 IgG-saporin Read More »

Genetic dissection of neural circuitry underlying REM sleep behavior disorder (RBD)

Wood DA, Patterson N, Fuller P, Sherman D, Saper C, Lu J (2007) Genetic dissection of neural circuitry underlying REM sleep behavior disorder (RBD). Neuroscience 2007 Abstracts 736.28/VV11. Society for Neuroscience, San Diego, CA. Summary: REM sleep behavior disorder (RBD), a parasomnia typically manifested as dream enactment behavior, may represent an early pathophysiologic manifestation of

Genetic dissection of neural circuitry underlying REM sleep behavior disorder (RBD) Read More »

Locus coeruleus (LC) is involved in sustaining arousal

Gompf HS, Fuller PM, Saper CB, Lu J (2007) Locus coeruleus (LC) is involved in sustaining arousal. Neuroscience 2007 Abstracts 736.3/UU16. Society for Neuroscience, San Diego, CA. Summary: The locus coeruleus (LC) has traditionally been thought to be involved in arousal; however, lesions of the LC have minimal effects on basal sleep-wake behavior. We propose

Locus coeruleus (LC) is involved in sustaining arousal Read More »

Organization of food protection behavior is differentially influenced by hippocampal and cortical cholinergic deafferentation

Martin MM, Carter LA, Jones JL, Winter SS, Wallace DG (2007) Organization of food protection behavior is differentially influenced by hippocampal and cortical cholinergic deafferentation. Neuroscience 2007 Abstracts 742.6/AAA9. Society for Neuroscience, San Diego, CA. Summary: Previous work has suggested that rats use temporal information to organize their food protection behaviors. Studies have demonstrated different

Organization of food protection behavior is differentially influenced by hippocampal and cortical cholinergic deafferentation Read More »

Selective hippocampal cholinergic deafferentation disrupts exploratory trip organization

Wallace DG, Knapp SK, Silver JA, Martin MM, Winter SS (2007) Selective hippocampal cholinergic deafferentation disrupts exploratory trip organization. Neuroscience 2007 Abstracts 743.17/BBB11. Society for Neuroscience, San Diego, CA. Summary: Rats organize their exploration of an environment around a central location or home base. Movements away from the home base are characterized as a series

Selective hippocampal cholinergic deafferentation disrupts exploratory trip organization Read More »

Effects of NBM lesions on selective attention in an interval timing task

McAuley J, Pang K (2007) Effects of NBM lesions on selective attention in an interval timing task. Neuroscience 2007 Abstracts 742.9. Society for Neuroscience, San Diego, CA. Summary: Divided and sustained attention are impaired by damage to the nucleus basalis magnocellularis (NBM), which provides cholinergic and GABAergic input to the neocortex. The present study was

Effects of NBM lesions on selective attention in an interval timing task Read More »

Hypocretin/orexin neuronal loss increases adult neurogenesis

Arias-Carrion O, Hernandez-Martinez H, Drucker-Colin R (2007) Hypocretin/orexin neuronal loss increases adult neurogenesis. Neuroscience 2007 Abstracts 456.14/C7. Society for Neuroscience, San Diego, CA. Summary: Adult neurogenesis in the subventricular zone (SVZ) is subjected to physiological regulation and can be modified by brain injuries. The sleep disorder narcolepsy may now be considered a neurodegenerative disease, as

Hypocretin/orexin neuronal loss increases adult neurogenesis Read More »

Ketamine-induced gating deficit of hippocampal auditory evoked potentials in rats is alleviated by medial septum inactivation and antipsychotic drugs

Ma J, Tai S, Leung LWS (2007) Ketamine-induced gating deficit of hippocampal auditory evoked potentials in rats is alleviated by medial septum inactivation and antipsychotic drugs. Neuroscience 2007 Abstracts 498.12/GG19. Society for Neuroscience, San Diego, CA. Summary: Gating of sensory responses is impaired in schizophrenic patients and animal models of schizophrenia. Ketamine, an N-methyl-D-aspartate receptor

Ketamine-induced gating deficit of hippocampal auditory evoked potentials in rats is alleviated by medial septum inactivation and antipsychotic drugs Read More »

Destruction of NPY receptor expressing neurons in the arcuate nucleus causes obesity and hyperphagia without increasing lateral hypothalamic orexigenic peptide gene expression

Li A-J, Dinh TT, Ritter S (2007) Destruction of NPY receptor expressing neurons in the arcuate nucleus causes obesity and hyperphagia without increasing lateral hypothalamic orexigenic peptide gene expression. Neuroscience 2007 Abstracts 524.20/BBB20. Society for Neuroscience, San Diego, CA. Summary: NPY-SAP, a conjugate of neuropeptide Y (NPY) and the ribosomal inactivating toxin, saporin (SAP), is

Destruction of NPY receptor expressing neurons in the arcuate nucleus causes obesity and hyperphagia without increasing lateral hypothalamic orexigenic peptide gene expression Read More »

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