Author name: Kristen Hartman

Walking the Plank: Role of the medial septum in distance estimation

Winter SS, Martin MM, Wallace DG (2007) Walking the Plank: Role of the medial septum in distance estimation. Neuroscience 2007 Abstracts 743.21/BBB15. Society for Neuroscience, San Diego, CA. Summary: Controversy surrounds the role of the septohippocampal system in spatial orientation. Recent work has demonstrated that selective cholinergic deafferentation of the hippocampus impairs use of self-movement […]

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Prefrontal cortical norepinephrine depletion does not impair spatial working memory in rats

King M, Jentsch JD (2007) Prefrontal cortical norepinephrine depletion does not impair spatial working memory in rats. Neuroscience 2007 Abstracts 645.16/CCC18. Society for Neuroscience, San Diego, CA. Summary: The midbrain dopamine neurons are thought to encode a reward prediction error signal (Schultz et al., 1997; Bayer & Glimcher, 2005). Parkinson’s disease (PD) is characterized by

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On the survival of nestin-expressing neurons in the cholinergic basal forebrain after an immunolesion with 192-IgG-saporin

Nguyen WT, Buhalog A, Hendrickson M, Kalil RE (2007) On the survival of nestin-expressing neurons in the cholinergic basal forebrain after an immunolesion with 192-IgG-saporin. Neuroscience 2007 Abstracts 674.5/D24. Society for Neuroscience, San Diego, CA. Summary: Nestin is a class VI intermediate filament protein that is widely accepted as a marker for uncommitted neural progenitor

On the survival of nestin-expressing neurons in the cholinergic basal forebrain after an immunolesion with 192-IgG-saporin Read More »

Neonatal cholinergic lesion and environmental enrichment:behavior, neurogenesis and CA1 cytoarchitecture

Frachette M, Rennie K, Pappas BA (2007) Neonatal cholinergic lesion and environmental enrichment:behavior, neurogenesis and CA1 cytoarchitecture. Neuroscience 2007 Abstracts 691.9/M9. Society for Neuroscience, San Diego, CA. Summary: The effects of neonatal cholinergic lesion and environmental enrichment on rat behaviour and hippocampal morphology were determined. Rats were injected with the immunotoxin 192 IgG- saporin (192S)

Neonatal cholinergic lesion and environmental enrichment:behavior, neurogenesis and CA1 cytoarchitecture Read More »

Behavioural consequences of combined cholinergic lesion and chronic cerebral hypoperfusion in rats

Rennie KE, Frechette M, Pappas BA (2007) Behavioural consequences of combined cholinergic lesion and chronic cerebral hypoperfusion in rats. Neuroscience 2007 Abstracts 698.16/R26. Society for Neuroscience, San Diego, CA. Summary: Chronic cerebral hypoperfusion compromises the health of hippocampal neurons, leading to a slowly emerging loss of pyramidal cells accompanied by spatial memory impairments in rats.

Behavioural consequences of combined cholinergic lesion and chronic cerebral hypoperfusion in rats Read More »

Progressive decrease in sleep deprivation-induced extracellular adenosine release and recovery NREM sleep following intracerebroventricular injection of 192 IgG-saporin

Kalinchuk AV, Porkka-Heiskanen T, McCarley RW, Basheer R (2007) Progressive decrease in sleep deprivation-induced extracellular adenosine release and recovery NREM sleep following intracerebroventricular injection of 192 IgG-saporin. Neuroscience 2007 Abstracts 735.10/TT29. Society for Neuroscience, San Diego, CA. Summary: The basal forebrain (BF) is an important site in the homeostatic regulation of sleep mediated by adenosine

Progressive decrease in sleep deprivation-induced extracellular adenosine release and recovery NREM sleep following intracerebroventricular injection of 192 IgG-saporin Read More »

Genetic dissection of neural circuitry underlying REM sleep behavior disorder (RBD)

Wood DA, Patterson N, Fuller P, Sherman D, Saper C, Lu J (2007) Genetic dissection of neural circuitry underlying REM sleep behavior disorder (RBD). Neuroscience 2007 Abstracts 736.28/VV11. Society for Neuroscience, San Diego, CA. Summary: REM sleep behavior disorder (RBD), a parasomnia typically manifested as dream enactment behavior, may represent an early pathophysiologic manifestation of

Genetic dissection of neural circuitry underlying REM sleep behavior disorder (RBD) Read More »

Locus coeruleus (LC) is involved in sustaining arousal

Gompf HS, Fuller PM, Saper CB, Lu J (2007) Locus coeruleus (LC) is involved in sustaining arousal. Neuroscience 2007 Abstracts 736.3/UU16. Society for Neuroscience, San Diego, CA. Summary: The locus coeruleus (LC) has traditionally been thought to be involved in arousal; however, lesions of the LC have minimal effects on basal sleep-wake behavior. We propose

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Organization of food protection behavior is differentially influenced by hippocampal and cortical cholinergic deafferentation

Martin MM, Carter LA, Jones JL, Winter SS, Wallace DG (2007) Organization of food protection behavior is differentially influenced by hippocampal and cortical cholinergic deafferentation. Neuroscience 2007 Abstracts 742.6/AAA9. Society for Neuroscience, San Diego, CA. Summary: Previous work has suggested that rats use temporal information to organize their food protection behaviors. Studies have demonstrated different

Organization of food protection behavior is differentially influenced by hippocampal and cortical cholinergic deafferentation Read More »

Selective hippocampal cholinergic deafferentation disrupts exploratory trip organization

Wallace DG, Knapp SK, Silver JA, Martin MM, Winter SS (2007) Selective hippocampal cholinergic deafferentation disrupts exploratory trip organization. Neuroscience 2007 Abstracts 743.17/BBB11. Society for Neuroscience, San Diego, CA. Summary: Rats organize their exploration of an environment around a central location or home base. Movements away from the home base are characterized as a series

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