• When or Why should you switch from using a secondary conjugate (like Fab-ZAP or Streptavidin-ZAP) to a direct saporin conjugate?
  • If you are working in vitro and using our secondary conjugates to specifically screening numerous targeting agents, then I would say “stay the course” and continue using these types of products. They are quick, effective and economical in screening antibodies.
  • However, if you are working in vivo and have been using our Streptavidin-ZAP to screen your biotinylated targeting agent, I would strongly suggest you contact us about performing a direct saporin conjugation.
  • Two reasons why you would want a direct conjugate:
    • 1st is Cost effectiveness. Streptavidin-ZAP is great at assessing your targeting agent, but when looking downstream at the cost to create bulk mg sized batches, a direct conjugate would provide double the yield with equivalent cost.
    • 2nd is Homogeneity. Since the targeting agent is directly-labeled with saporin, we end up with a product that is more homogeneous versus a conjugate made with various components and various labeling.
  • Learn more
  • 20% off your order of a custom saporin conjugation.
  • Use discount code TUESDAYTIP5 for 20% off.
  • Contact us to discuss your targeting project.

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