Targeting Trends Newsletter 11q2

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page.


Newsletter Highlights

  • Basigin-2 poster (page 2)
  • Teaser Winners (page 2)
  • Customs, Conjugates, and Toxicity (page 5)
  • Featured Recombinant Proteins (page 7)
  • Complete and Submit the Targeting Teaser online!

Carrageenan evoked P-Akt in deep dorsal horn neurons is prevented by loss of neurokinin1 positive neurons in superficial dorsal horn – read article
(continued on page 6)

Contributed by L.S. Sorkin, J.-I. Choi, and F.J. Koehrn, Univ. California San Diego, La Jolla, CA

Product information related to cover article: SSP-SAP (Cat. #IT-11)

Basigin-2 (EMMPRIN), a Prognostic Marker, is a Dynamic Portal of Entry into Cancer Cells (read article)

by Leonardo R. Ancheta and Douglas A. Lappi, American Association of Cancer Research abstract #5218

Product information related to article: Anti-Basigin2-SAP (Cat. #IT-54)

Upcoming Events

  • Amer Assoc of Immunologists / May 13-17, 2011 / San Francisco, CA / Booth #426
  • American Pain Society / May 18-21, 2011 / Austin, TX / Booth #229
  • International Brain Res Org / July 14-18, 2011 / Florence, Italy / Booth #12

Targeting Teaser Winners

Recent Scientific References (read online)

  • Antonini V, Marrazzo A, Kleiner G, Coradazzi M, Ronsisvalle S, Prezzavento O, Ronsisvalle G, Leanza G. (2011) Anti-Amnesic and Neuroprotective Actions of the Sigma-1 Receptor Agonist (-)-MR22 in Rats with Selective Cholinergic Lesion and Amyloid Infusion. J Alzheimers Dis (Cat. #IT-01)
  • Chen AI, Nguyen CN, Copenhagen DR, Badurek S, Minichiello L, Ranscht B, Reichardt LF. (2011) TrkB (Tropomyosin-Related Kinase B) Controls the Assembly and Maintenance of GABAergic Synapses in the Cerebellar Cortex. J Neurosci 31(8):2769-2780. (Cat. #AB-N32)
  • Gibbs RB, Chipman AM, Nelson D. (2011) Donepezil plus estradiol treatment enhances learning and delay-dependent memory performance by young ovariectomized rats with partial loss of septal cholinergic neurons. Horm Behav (Cat. #IT-01)
  • Girard BM, Malley SE, Vizzard MA. (2011) Neurotrophin/receptor expression in urinary bladder of mice with overexpression of NGF in urothelium. Am J Physiol Renal Physiol 300(2):F345-55. (Cat. #AB-N01)
  • Hernandez-Melesio MA, Gonzalez-Esquivel D, Ortiz-Plata A, Sanchez-Mendoza A, Sanchez-Garcia A, Alcaraz-Zubeldia M, Rios C, Perez-Severiano F. (2011) Molsidomine modulates the cNOS activity in an experimental model of cholinergic damage induced by 192-IgG saporin. Neurosci Lett 491(2):133-137. (Cat. #IT-01)
  • I’anson H, Jethwa PH, Warner A, Ebling FJ. (2011) Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters. Physiol Behav (Cat. # IT-20, Cat. #PR-01)
  • Leung LS, Petropoulos S, Shen B, Luo T, Herrick I, Rajakumar N, Ma J. (2011) Lesion of cholinergic neurons in nucleus basalis enhances response to general anesthetics. Exp Neurol (Cat. # IT-01)
  • Chung JS, Shiue LH, Duvic M, Pandya A, Cruz PDJ, Ariizumi K. (2011) Sezary syndrome cells overexpress syndecan-4 bearing distinct heparan sulfate moieties that suppress T-cell activation by binding DC-HIL and trapping TGF-{beta} on the cell surface. Blood 117(12):3382-3390. (Cat. #IT-27)
  • Heldmann U, Mine Y, Kokaia Z, Ekdahl CT, Lindvall O. (2011) Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke. Exp Neurol (Cat. #IT-33)
  • Lee S, Craddock Z, Rivier C. (2011) Brain stem catecholamines circuitry: Activation by alcohol and role in the hypothalamic-pituitary-adrenal response to this drug. J Neuroendocrinol (Cat. #IT-03)
  • Montandon G, Qin W, Liu H, Ren J, Greer JJ, Horner RL. (2011) PreBotzinger complex neurokinin-1 receptor-expressing neurons mediate opioid-induced respiratory depression. J Neurosci 31(4):1292-1301. (Cat. #AB-N04)
  • Paban V, Chambon C, Farioli F, Alescio-Lautier B. (2011) Gene regulation in the rat prefrontal cortex after learning with or without cholinergic insult. Neurobiol Learn Mem (Cat. #IT-01)
  • Sawada R, Sun SM, Wu X, Hong F, Ragupathi G, Livingston PO, Scholz WW. (2011) Human Monoclonal Antibodies to Sialyl-Lewisa (CA19.9) with Potent CDC, ADCC, and Antitumor Activity. Clin Cancer Res 17(5):1024-1032. (Cat. #IT-22)
  • Wagle M, Mathur P, Guo S. (2011) Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol. J Neurosci 31(1):214-224. (Cat. #AB-02)
  • Li AJ, Wang Q, Ritter S. (2011) Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding. Diabetes 60(2):436-442. (Cat. #IT-03, Cat. #PR-01)
  • Takasusuki T, Yaksh TL. (2011) The effects of intrathecal and systemic gabapentin on spinal substance P release. Anesth Analg 112(4):971-976. (Cat. #AB-N04)

Targeting Talk (see text)

ATS Welcomes Our Newest Members to the Targeting Team!

Targeting Tools: Featured Recombinant Proteins

Gangsta Gallery

Targeting Technology Tutorial

Targeting Teaser (Jumble)