Targeting Trends Newsletter 11q2

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Newsletter Highlights

  • Basigin-2 poster (page 2)
  • Teaser Winners (page 2)
  • Customs, Conjugates, and Toxicity (page 5)
  • Featured Recombinant Proteins (page 7)
  • Complete and Submit the Targeting Teaser online!

Carrageenan evoked P-Akt in deep dorsal horn neurons is prevented by loss of neurokinin1 positive neurons in superficial dorsal horn – read article
(continued on page 6)

Contributed by L.S. Sorkin, J.-I. Choi, and F.J. Koehrn, Univ. California San Diego, La Jolla, CA

Product information related to cover article: SSP-SAP (Cat. #IT-11)

Basigin-2 (EMMPRIN), a Prognostic Marker, is a Dynamic Portal of Entry into Cancer Cells (read article)

by Leonardo R. Ancheta and Douglas A. Lappi, American Association of Cancer Research abstract #5218

Product information related to article: Anti-Basigin2-SAP (Cat. #IT-54)

Upcoming Events

  • Amer Assoc of Immunologists / May 13-17, 2011 / San Francisco, CA / Booth #426
  • American Pain Society / May 18-21, 2011 / Austin, TX / Booth #229
  • International Brain Res Org / July 14-18, 2011 / Florence, Italy / Booth #12

Targeting Teaser Winners

Recent Scientific References (read online)

  • Antonini V, Marrazzo A, Kleiner G, Coradazzi M, Ronsisvalle S, Prezzavento O, Ronsisvalle G, Leanza G. (2011) Anti-Amnesic and Neuroprotective Actions of the Sigma-1 Receptor Agonist (-)-MR22 in Rats with Selective Cholinergic Lesion and Amyloid Infusion. J Alzheimers Dis (Cat. #IT-01)
  • Chen AI, Nguyen CN, Copenhagen DR, Badurek S, Minichiello L, Ranscht B, Reichardt LF. (2011) TrkB (Tropomyosin-Related Kinase B) Controls the Assembly and Maintenance of GABAergic Synapses in the Cerebellar Cortex. J Neurosci 31(8):2769-2780. (Cat. #AB-N32)
  • Gibbs RB, Chipman AM, Nelson D. (2011) Donepezil plus estradiol treatment enhances learning and delay-dependent memory performance by young ovariectomized rats with partial loss of septal cholinergic neurons. Horm Behav (Cat. #IT-01)
  • Girard BM, Malley SE, Vizzard MA. (2011) Neurotrophin/receptor expression in urinary bladder of mice with overexpression of NGF in urothelium. Am J Physiol Renal Physiol 300(2):F345-55. (Cat. #AB-N01)
  • Hernandez-Melesio MA, Gonzalez-Esquivel D, Ortiz-Plata A, Sanchez-Mendoza A, Sanchez-Garcia A, Alcaraz-Zubeldia M, Rios C, Perez-Severiano F. (2011) Molsidomine modulates the cNOS activity in an experimental model of cholinergic damage induced by 192-IgG saporin. Neurosci Lett 491(2):133-137. (Cat. #IT-01)
  • I’anson H, Jethwa PH, Warner A, Ebling FJ. (2011) Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters. Physiol Behav (Cat. # IT-20, Cat. #PR-01)
  • Leung LS, Petropoulos S, Shen B, Luo T, Herrick I, Rajakumar N, Ma J. (2011) Lesion of cholinergic neurons in nucleus basalis enhances response to general anesthetics. Exp Neurol (Cat. # IT-01)
  • Chung JS, Shiue LH, Duvic M, Pandya A, Cruz PDJ, Ariizumi K. (2011) Sezary syndrome cells overexpress syndecan-4 bearing distinct heparan sulfate moieties that suppress T-cell activation by binding DC-HIL and trapping TGF-{beta} on the cell surface. Blood 117(12):3382-3390. (Cat. #IT-27)
  • Heldmann U, Mine Y, Kokaia Z, Ekdahl CT, Lindvall O. (2011) Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke. Exp Neurol (Cat. #IT-33)
  • Lee S, Craddock Z, Rivier C. (2011) Brain stem catecholamines circuitry: Activation by alcohol and role in the hypothalamic-pituitary-adrenal response to this drug. J Neuroendocrinol (Cat. #IT-03)
  • Montandon G, Qin W, Liu H, Ren J, Greer JJ, Horner RL. (2011) PreBotzinger complex neurokinin-1 receptor-expressing neurons mediate opioid-induced respiratory depression. J Neurosci 31(4):1292-1301. (Cat. #AB-N04)
  • Paban V, Chambon C, Farioli F, Alescio-Lautier B. (2011) Gene regulation in the rat prefrontal cortex after learning with or without cholinergic insult. Neurobiol Learn Mem (Cat. #IT-01)
  • Sawada R, Sun SM, Wu X, Hong F, Ragupathi G, Livingston PO, Scholz WW. (2011) Human Monoclonal Antibodies to Sialyl-Lewisa (CA19.9) with Potent CDC, ADCC, and Antitumor Activity. Clin Cancer Res 17(5):1024-1032. (Cat. #IT-22)
  • Wagle M, Mathur P, Guo S. (2011) Corticotropin-releasing factor critical for zebrafish camouflage behavior is regulated by light and sensitive to ethanol. J Neurosci 31(1):214-224. (Cat. #AB-02)
  • Li AJ, Wang Q, Ritter S. (2011) Participation of hindbrain AMP-activated protein kinase in glucoprivic feeding. Diabetes 60(2):436-442. (Cat. #IT-03, Cat. #PR-01)
  • Takasusuki T, Yaksh TL. (2011) The effects of intrathecal and systemic gabapentin on spinal substance P release. Anesth Analg 112(4):971-976. (Cat. #AB-N04)

Targeting Talk (see text)

ATS Welcomes Our Newest Members to the Targeting Team!

Targeting Tools: Featured Recombinant Proteins

Gangsta Gallery

Targeting Technology Tutorial

Targeting Teaser (Jumble)