Targeting Trends Newsletter 11q1

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Newsletter Highlights

  • SFN Poster Winners (page 2)
  • Teaser Winners (page 2)
  • Anti-M-ZAP; IgM Controls; GAT1-SAP (page 5)
  • Anti-DBH-SAP (page 7)
  • Complete and Submit the Targeting Teaser online!

Targeted Lesion of Caudal Brainstem Catecholamine Neurons Reveals Their Role in Symptoms of Fatigue – read article (references on page 5, continued on page 6)

Contributed by Lisa E. Goehler and Ronald P.A. Gaykema
Center for the Study of Complementary and Alternative Therapies, University of Virginia School of Nursing, Charlottesville, VA 22908

Product information related to cover article: Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18)

2010 Society for Neuroscience Poster Award Winner

  • “Functional cholinergic neurons from human embryonic stem cells.”
    Presented by Y. Liu, R. Krencik, H. Liu, L. Ma, X. Zhang, S.-C. Zhang; Univ Wisconsin
    Featuring mu p75-SAP (Cat. #IT-16)
  • Runner-up: “Carageenan evoked P-Akt in deep dorsal horn neurons is prevented by loss of neurokinin1 positive neurons in superficial dorsal horn.”
    Presented by L.S. Sorkin, J.-I. Choi, F.J. Koehrn; Univ Calif San Diego
    Featuring SSP-SAP (Cat. #IT-11)
  • Runner-up: “Early post-natal cholinergic lesion impairs normal development and maturation of the motor cortex in rats.”
    Presented by D. Ramanathan, J.M. Conner, A.A. Anilkumar, M.H. Tuszynski; Univ Calif San Diego
    Featuring 192-IgG-SAP (Cat. #IT-01)
  • More SFN abstracts

Targeting Teaser Winners

Upcoming Events

  • American Association for Cancer Research (AACR); Booth #2278 • April 2-6, 2011 • Orlando, FL
  • Experimental Biology • April 9-13, 2011 • Washington, DC

Recent Scientific References (read online)

  • Gompf HS, Mathai C, Fuller PM, Wood DA, Pedersen NP, Saper CB, Lu J (2010) Locus ceruleus and anterior cingulate cortex sustain wakefulness in a novel environment J Neurosci 30(43):14543-14551. (Cat. #IT-03)
  • Gray PA, Hayes JA, Ling GY, Llona I, Tupal S, Picardo MCD, Ross SE, Hirata T, Corbin JG, Eugen n J, Del Negro CA (2010) Developmental origin of preB tzinger Complex respiratory neurons J Neurosci 30(44):14883-14895. (Cat. #AB-N04)
  • Lyons AM, Thiele TE (2010) Neuropeptide Y conjugated to saporin alters anxiety-like behavior when injected into the central nucleus of the amygdala or basomedial hypothalamus in BALB/cJ mice Peptides 31(12):2193-2199. (Cat. #IT-28; Cat. #IT-21)
  • Quadros EV, Nakayama Y, Sequeira JM (2010) Targeted delivery of saporin toxin by monoclonal antibody to the transcobalamin receptor, TCblR/CD320 Mol Cancer Ther 9(11):3033-3040. (Cat. #IT-04)
  • Yang MY, Chaudhary A, Seaman S, Dunty J, Stevens J, Elzarrad MK, Frankel AE, St Croix B (2011) The Cell Surface Structure of Tumor Endothelial Marker 8 (TEM8) is Regulated by the Actin Cytoskeleton Biochim Biophys Acta 1813(1):39-49. (Cat. #IT-27)
  • Di Sebastiano AR, Wilson-Perez HE, Lehman MN, Coolen LM (2011) Lesions of orexin neurons block conditioned place preference for sexual behavior in male rats Horm Behav 59(1):1-8. (Cat. #IT-20; Cat. #IT-21)
  • Gil-Bea FJ, Solas M, Mateos L, Winblad B, Ram rez MJ, Cedazo-M nguez A (2010) Cholinergic hypofunction impairs memory acquisition possibly through hippocampal Arc and BDNF downregulation Hippocampus :. (Cat. #IT-01)
  • Klinkenberg I, Sambeth A, Blokland A (2010) Acetylcholine and attention Behav Brain Res :. (Cat. #IT-01; Cat. #IT-16)
  • Koenig J, Lecourtier L, Cosquer B, Pereira PM, Cassel J (2010) Spatial memory alterations by activation of septal 5HT(1A) receptors: no implication of cholinergic septohippocampal neurons Psychopharmacology (Berl) :. (Cat. #IT-01)
  • Laplante F, Lappi DA, Sullivan RM (2010) Cholinergic depletion in the nucleus accumbens: Effects on amphetamine response and sensorimotor gating Prog Neuropsychopharmacol Biol Psychiatry :. (Cat. #IT-42; Cat. #IT-35)
  • Pang KCH, Jiao X, Sinha S, Beck KD, Servatius RJ (2010) Damage of GABAergic neurons in the medial septum impairs spatial working memory and extinction of active avoidance: Effects on proactive interference Hippocampus :. (Cat. #IT-32)
  • Rennie K, Fr ©chette M, Pappas BA (2010) The effects of neonatal forebrain cholinergic lesion on adult hippocampal neurogenesis Brain Res :. (Cat. #IT-01)
  • Cerminara NL (2010) Cerebellar modules: individual or composite entities? J Neurosci 30(48):16065-16067. (Cat. #IT-14)
  • Do MTH, Yau K (2010) Intrinsically photosensitive retinal ganglion cells Physiol Rev 90(4):1547-1581. (Cat. #IT-44)

Targeting Talk (see text)

References from Cover Article (see page 1 and page 6)

Targeted Lesion of Caudal Brainstem Catecholamine Neurons Reveals Their Role in Symptoms of Fatigue
(continued from page 1, references on page 5)

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