Targeting Trends Newsletter 09q2

Below are links to view the quarterly newsletter Targeting Trends. If you would like to be added to the mailing list, please complete the information on our contact page.

Newsletter Highlights

  • Spring Sighting (page 2)
  • New Digs (page 2)
  • Teaser Winners (page 5)
  • CTB-SAP, Hug-M-ZAP (page 7)
  • Complete and Submit the Targeting Teaser online!

Deletion of Catecholaminergic Neurons by Anti-DBH-Saporin Disrupts Hypothalamic MAP Kinase and CREB Activation – read article (continued on page 6)

Contributed by Arshad M. Khan, Kimberly L. Rapp, Todd A. Ponzio, Graciela Sanchez-Watts and Alan G. Watts, Dept. of Biological Sciences and Neuroscience Research Institute, University of Southern California, Los Angeles, CA; and Laboratory for Neurochemistry, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD. 2008 SfN Poster Award Winner.Product information related to cover article: Anti-DBH-SAP (Cat. #IT-03), Mouse IgG-SAP (Cat. #IT-18)

Spring is Here! (Gangsta’s baby hummingbirds)

New Facility

Recent Scientific References – read online

  • Brightwell JJ, Taylor BK (2009) Noradrenergic Neurons in the Locus Coeruleus Contribute to Neuropathic Pain. Neuroscience 160:174-185. (Cat. #IT-03; Cat. #IT-18)
  • Cutuli D, Foti F, Mandolesi L, De Bartolo P, Gelfo F, Federico F, Petrosini L (2009) Cognitive Performances of Cholinergically Depleted Rats Following Chronic Donepezil Administration. J Alzheimers Dis [Epub]. (Cat. #IT-01)
  • Rivat C, Vera-Portocarrero LP, Ibrahim MM, Mata HP, Stagg NJ, De Felice M, Porreca F, Malan TP (2009) Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain. Eur J Neurosci 29:727-737. (Cat. #IT-07; Cat. #PR-01)
  • Bogen O, Dina OA, Gear RW, Levine JD (2009) Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. Neuroscience 159:780-786. (Cat. #IT-10)
  • Nag N, Baxter MG, Berger-Sweeney JE (2009) Efficacy of a murine-p75-saporin immunotoxin for selective lesions of basal forebrain cholinergic neurons in mice. Neurosci Lett 452:247-251. (Cat. #IT-16)
  • Wiley RG, Lemons LL, Kline RH (2008) Neuropeptide Y receptor-expressing dorsal horn neurons: Role in nocifensive reflex responses to heat and formalin. Neuroscience 161:139-147. (Cat. #IT-28; Cat. #IT-21)
  • Frechette M, Rennie K, Pappas BA (2009) Developmental forebrain cholinergic lesion and environmental enrichment: behaviour, CA1 cytoarchitecture and neurogenesis. Brain Res 1252:172-182. (Cat. #IT-01)
  • Tronson NC, Schrick C, Guzman YF, Huh KH, Srivastava DP, Penzes P, Guedea AL, Gao C, Radulovic J (2009) Segregated populations of hippocampal principal CA1 neurons mediating conditioning and extinction of contextual fear. J Neurosci 29:3387-3394. (Cat. #IT-16; Cat. #PR-01)
  • Nayate A, Moore SA, Weiss R, Taktakishvili OM, Lin LH, Talman WT (2009) Cardiac damage after lesions of the nucleus tractus solitarii. Am J Physiol Regul Integr Comp Physiol 296:R272-279. (Cat. #IT-11)
  • Little CM, Coons KD, Sengelaub DR (2009) Neuroprotective effects of testosterone on the morphology and function of somatic motoneurons following the death of neighboring motoneurons. J Comp Neurol 512:359-372. (Cat. #IT-14)
  • McGaughy J, Ross RS, Eichenbaum H (2008) Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting. Neuroscience 153:63-71. (Cat. #IT-03; Cat. #IT-01)
  • Loyd DR, Wang X, Murphy AZ (2008) Sex differences in micro-opioid receptor expression in the rat midbrain periaqueductal gray are essential for eliciting sex differences in morphine analgesia. J Neurosci 28:14007-14017. (Cat. #IT-12; Cat. #IT-21)
  • Truitt WA, Johnson PL, Dietrich AD, Fitz SD, Shekhar A (2009) Anxiety-like behavior is modulated by a discrete subpopulation of interneurons in the basolateral amygdala. Neuroscience 160:284-294. (Cat. #IT-11)
  • Lujan HL, Palani G, Chen Y, Peduzzi-Nelson J, Dicarlo SE (2009) Targeted Ablation of Cardiac Sympathetic Neurons Reduces Resting, Reflex and Exercise-Induced Sympathetic Activation in Conscious Rats. Am J Physiol Heart Circ Physiol 296:H1305-H1311. (Cat. #IT-14)
  • Young B, Coolen L, McKenna K (2009) Neural regulation of ejaculation. J Sex Med 6 Suppl 3:229-233. (Cat. #IT-11)

Targeting Talk (see text)

Upcoming Events

  • American Association of Immunologists • Seattle, WA — May 8-12, 2009 — Booth #208
  • Society for Neuroscience • Chicago, IL — October 17-21, 2009

Featured Antibodies

Targeting Tools: Featured Products

Gangsta Gallery

Targeting Technology Tutorial