Streptavidin-ZAP (Cat. #IT-27)
Saporin conjugated to streptavidin is one of the most useful reagents that we have produced at ATS. It has been used in a wide variety of studies both in academic research and pharmaceutical/biotech labs. Workers are able to easily see if their molecule, that is biotinylated, is internalized by the target cells. The simple read-out of cell death requires only a microscope, but is also easily scaled up for industrial use. The streptavidin-biotin bond is so strong that streptavidin-ZAP can even be used in vivo. The technique can be used with all sorts of molecules: growth factors, peptide ligands, cytokines, antibodies—anything that can be biotinylated. Can’t biotinylate it? Then let us do it for you!