Anti-CD63-SAP [IT-99, KIT-99]

Name: Anti-CD63-SAP [IT-99, KIT-99]
SKU: IT-99
Availability: InStock

a tool for eliminating cells that express human CD63; targeted via a mouse monoclonal antibody to human CD63, eliminated via saporin

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SKU: IT-99 Category: Targeted Toxins Quantity: Individual 25 ug, Individual 100 ug, Individual 250 ug, Individual 1 mg, Kit w/controls 25 ug, Kit w/controls 100 ug, Kit w/controls 250 ug | Antibody Type: Monoclonal | Host: mouse | Reactivity: human | Conjugate: saporin | Usage: eliminates cells |

CD63 is a protein that is expressed on the surface of various cell types, including certain immune cells (such as T-cells, B-cells, and macrophages), and tumor cells. CD63 is a member of the tetraspanin family of proteins, which are involved in processes like cell adhesion, endocytosis, signal transduction, and the formation of exosomes.

Anti-CD63-SAP is a chemical conjugate of the antibody to CD63 and the ribosome-inactivating protein, saporin.

Anti-CD63-SAP is available individually (Cat. #IT-99) or as a kit (Cat. #KIT-99) which includes Anti-CD63-SAP and Mouse IgG-SAP (Cat. #IT-18).

keywords: CD63, immune cells, T-cell, B-cell, macrophage, tumor, tetraspanin, adhesion, endocytosis, signal transduction, exosomes, saporin, targeted toxin

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View Data Sheet

Identification of lineage-specific markers for therapeutic targeting of mast cells.

Plum T (2019) Identification of lineage-specific markers for therapeutic targeting of mast cells. Ruperto-Carola University of Heidelberg, Germany Thesis. doi: 10.11588/heidok.00023555

Usage: Mice were injected i.v. with either 100 µg of 1:1 molar mixture of biotinylated CD63 antibody and Streptavidin-ZAP (60 µg mAb + 40 µg SAP) or with 40 µg SAP alone. All injections were performed in 200 µl PBS.

Related Products: Streptavidin-ZAP (Cat. #IT-27), Saporin (Cat. #PR-01), Anti-CD63-SAP (Cat. #IT-99)