Anti-FLAG (M5)-SAP [IT-59, KIT-59]

a tool for eliminating FLAG (M5)-expressing cells; targeted via mouse monoclonal antibody to N-terminal Met-FLAG fusion protein, eliminated via saporin

SKU: IT-59 Category: Antibody Type: Monoclonal | Host: mouse |Conjugate: saporin | Usage: eliminates cells |

A fusion tag called FLAG consists of eight amino acids (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys). FLAG is specifically designed for immunoaffinity chromatography. It allows elution under non-denaturing conditions. Several antibodies against this peptide have been developed. One antibody denoted as M5 detects N-terminal Met-FLAG fusion proteins.

Anti-FLAG (M5)-SAP is a chemical conjugate of a mouse monoclonal antibody to the N-terminal Met-FLAG fusion protein and the ribosome-inactivating protein, saporin. It specifically eliminates cells with extracellular expression of FLAG-tagged proteins and cells that recognize YOUR FLAG-tagged recombinant proteins.

Anti-FLAG (M5)-SAP is available individually (Cat. #IT-59) or as a kit (Cat. #KIT-59) which includes Anti-FLAG (M5)-SAP and Mouse IgG-SAP (Cat. #IT-18).