Galanin-SAP [IT-34, KIT-34]

a tool for eliminating cells that express galanin-1 receptor; targeted via rat galanin, eliminated via saporin

SKU: IT-34 Category: Quantity: Individual 25 ug, Individual 100 ug, Individual 250 ug, Individual 1 mg, Kit w/controls 25 ug, Kit w/controls 100 ug, Kit w/controls 250 ug | Host: rat | Conjugate: saporin | Usage: eliminates cells |

Galanin is a 29-amino acid peptide (30 amino acids in humans) implicated in a variety of functions including nociception, appetite, learning, and memory. It is widely distributed throughout the neural and endocrine systems, playing roles in the secretion of insulin, somatostatin, glucagon, dopamine, and growth hormone, and inhibiting the release of acetylcholine and substance P from myenteric neurons. Galanin-SAP eliminates cells expressing the galanin-1 receptor. It is not suitable for retrograde transport.

Galanin-SAP is a chemical conjugate of rat galanin and the ribosome-inactivating protein, saporin. It eliminates cells expressing the galanin-1 receptor.

Galanin-SAP is available individually (Cat. #IT-34) or as a kit (Cat. #KIT-34) which includes Galanin-SAP and Blank-SAP (Cat. #IT-21).

keywords: galanin, galanin-1 receptor, acetylcholine, substance P, SP, saporin, Somatostatin-positive interneurons, neurons, globus pallidus and thalamus


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