Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone, is a peptide responsible for the release of follicle-stimulating hormone and luteinizing hormone from the anterior pituitary. This cascade is critical for reproductive functions. GnRH is expressed in the hypothalamus, and the receptors for this peptide are found in the pituitary gland. GnRH and its receptors can also be found in cancers of the breast, ovary, prostate, and endometrium. GnRH-SAP could be used to study reproductive functions and some cancer types.
GnRH-SAP specifically eliminates cells expressing GnRH receptors.
The following control is included for validating the specificity of the beta conjugate: Blank-SAP (Cat. #IT-21).
This product is being offered as part of our Beta Testing program. It has saporin activity confirmed, peptide sequences published/confirmed, and/or antibody binding specificity published/confirmed. It has not been characterized or reported in scientific literature. The researcher who first publishes data* will receive a $500 credit for use on ATS products.
*Data subject to review by the scientific team at ATS. See complete details here.