Anti-MC4R-SAP [BETA-020]


[affinity-purified anti-human MC4R]-streptavidin-saporin
This kit includes 25 ug Anti-MC4R-SAP Kit (BETA-020), 25 ug BIgG-SAP Rabbit (IT-75)

SKU: BETA-020 Category: Quantity: 25 ug | Antibody Type: affinity-purified, Polyclonal | Host: rabbit | Reactivity: human, rat | Conjugate: streptavidin-saporin | Usage: eliminates cells, retrograde transport |

The melanocortin receptor 4 (MC4R) is a G-protein-coupled receptor that specifically binds melanocyte stimulating hormones (α, β, γ-MSH). Studies in murine models have shown these receptors to be involved in energy homeostasis, feeding behavior, sexual behavior, and male erectile function. With obesity in humans now also becoming such a problem, this receptor has become a topic of interest because of its involvement in related aspects such as insulin resistance, fat mass, weight and risk of obesity.

Anti-MC4R-SAP eliminates cells expressing human or rat MC4R.

The following control is included for validating the specificity of the beta conjugate: BIgG-SAP rabbit (Cat. #IT-75).

This product is being offered as part of our Beta Testing program. It has saporin activity confirmed, peptide sequences published/confirmed, and/or antibody binding specificity published/confirmed. It has not been characterized or reported in scientific literature. The researcher who first publishes data* will receive a $500 credit for use on ATS products.

*Data subject to review by the scientific team at ATS. See complete details here.

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