- Home
- Knowledge Base
- History of Saporin
History of Saporin
Specific domains of ß-amyloid from Alzheimer plaque elicit neuron killing in human microglia.
Giulian D, Haverkamp LJ, Yu JH, Karshin W, Tom D, Li J, Kirkpatrick J, Kuo YM, Roher AE (1996) Specific domains of ß-amyloid from Alzheimer plaque elicit neuron killing in human microglia. J Neurosci 16:6021-6037. doi: 10.1523/JNEUROSCI.16-19-06021.1996 PMID: 8815885
Related Products: Acetylated LDL-SAP (Cat. #IT-08)
Destruction of the cholinergic basal forebrain using immunotoxin to rat NGF receptor: modeling the cholinergic degeneration of Alzheimer’s disease.
Wiley RG, Berbos T, Deckwerth T, Johnson EM, Lappi DA (1995) Destruction of the cholinergic basal forebrain using immunotoxin to rat NGF receptor: modeling the cholinergic degeneration of Alzheimer’s disease. J Neurol Sci 128:157-166. doi: 10.1016/0022-510x(94)00226-e PMID: 7738592
Related Products: 192-IgG-SAP (Cat. #IT-01)
Noradrenergic lesioning with an anti-dopamine beta-hydroxylase immunotoxin.
Picklo MJ, Wiley RG, Lappi DA, Robertson D (1994) Noradrenergic lesioning with an anti-dopamine beta-hydroxylase immunotoxin. Brain Res 666:195-200. doi: 10.1016/0006-8993(94)90772-2
Related Products: Anti-DBH-SAP (Cat. #IT-03)
The expression of saporin, a ribosome-inactivating protein from the plant Saponaria officinalis, in Escherichia coli
Barthelemy I, Martineau D, Ong M, Matsunami R, Ling N, Benatti L, Cavallaro U, Soria M, Lappi DA (1993) The expression of saporin, a ribosome-inactivating protein from the plant Saponaria officinalis, in Escherichia coli. J Biol Chem 268(9):6541-6548.
Immunolesioning: Selective destruction of neurons using immunotoxin to rat NGF receptor.
Wiley RG, Oeltmann TN, Lappi DA (1991) Immunolesioning: Selective destruction of neurons using immunotoxin to rat NGF receptor. Brain Res 562:149-153. doi: 10.1016/0006-8993(91)91199-b
Related Products: 192-IgG-SAP (Cat. #IT-01)
Selective elimination of fibroblasts from pancreatic islet monolayers by basic fibroblast growth factor-saporin mitotoxin.
Beattie GM, Lappi DA, Baird A, Hayek A (1990) Selective elimination of fibroblasts from pancreatic islet monolayers by basic fibroblast growth factor-saporin mitotoxin. Diabetes 39:1002-1005. doi: 10.2337/diab.39.8.1002
Related Products: FGF-SAP (Cat. #IT-38)
Anti-Thy-1 immunotoxin, OX7-saporin, destroys cerebellar Purkinje cells after intraventricular injection in rats.
Davis TL, Wiley RG (1989) Anti-Thy-1 immunotoxin, OX7-saporin, destroys cerebellar Purkinje cells after intraventricular injection in rats. Brain Res 504:216-222. doi: 10.1016/0006-8993(89)91360-7
Related Products: OX7-SAP (Cat. #IT-02)
Bispecific F(ab’ gamma)2 antibody for the delivery of saporin in the treatment of lymphoma
Glennie MJ, Brennand DM, Bryden F, McBride HM, Stirpe F, Worth AT, Stevenson GT (1988) Bispecific F(ab’ gamma)2 antibody for the delivery of saporin in the treatment of lymphoma. J Immunol 141(10):3662-3670.
Evaluation of antihuman T lymphocyte saporin immunotoxins potentially useful in human transplantation
Siena S, Bregni M, Formosa A, Martineau D, Lappi DA, Bonadonna G, Gianni AM (1988) Evaluation of antihuman T lymphocyte saporin immunotoxins potentially useful in human transplantation. Transplantation 46(5):747-753. doi: 10.1097/00007890-198811000-00023
The mechanism of action of barley toxin: a type 1 ribosome-inactivating protein with RNA N-glycosidase activity
Endo Y, Tsurugi K, Ebert RF (1988) The mechanism of action of barley toxin: a type 1 ribosome-inactivating protein with RNA N-glycosidase activity. Biochim Biophys Acta 954(2):224-226. doi: 10.1016/0167-4838(88)90075-1