- Home
- Knowledge Base
- antibodies
antibodies
Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat.
Gerashchenko D, Kohls MD, Greco M, Waleh NS, Salin-Pascual R, Kilduff TS, Lappi DA, Shiromani PJ (2001) Hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat. J Neurosci 21(18):7273-7283. doi: 10.1523/JNEUROSCI.21-18-07273.2001 PMID: 11549737
Summary: Orexin (also knows as hypocretin) peptides are produced exclusively by neurons in the lateral hypothalamus, however non-specific lesioning in this region has not produced narcoleptic-like sleep. Gerashchenko et al. use orexin-SAP (490 ng/0.5 µl; Cat. #IT-20) to specifically eliminate orexin neurons in rats. The treated rats displayed several sleep disturbances found in narcolepsy, including increased slow-wave sleep, and sleep-onset REM sleep periods. The data suggest that orexin-SAP can be used to create a model for narcolepsy in rats.
Related Products: Orexin-B-SAP (Cat. #IT-20), Saporin Goat Polyclonal, affinity-purified FITC-labeled (Cat. #AB-15APFL), Saporin Chicken Polyclonal, affinity-purified (Cat. #AB-17AP)
Immunohistochemical localization of AT-1A and AT-1B angiotensin II receptor subtypes in the rat adrenal
Speth RC, Grove KL, Brownfield MS (2001) Immunohistochemical localization of AT-1A and AT-1B angiotensin II receptor subtypes in the rat adrenal. Endocrine Society ENDO 2001 – 83rd Annual Meeting of the Endocrine Society, Denver, Colorado. PMID: 909090
Related Products: Angiotensin II receptor (AT-1AR) Rabbit Polyclonal, affinity-purified (Cat. #AB-N25AP)
Assessment of protein gene product 9.5 as a marker of neural crest-derived precursor cells in the developing enteric nervous system.
Sidebotham EL, Woodward MN, Kenny SE, Lloyd DA, Vaillant CR, Edgar DH (2001) Assessment of protein gene product 9.5 as a marker of neural crest-derived precursor cells in the developing enteric nervous system. Pediatr Surg Int 17:304-307. doi: 10.1007/s003830100599 PMID: 11409167
Related Products: Antibody to NGFR (Cat. #AB-N02)
Mesenchymal cell precursors of peritubular smooth muscle cells of the mouse testis can be identified by the presence of the p75 neurotrophin receptor.
Campagnolo L, Russo MA, Puglianiello A, Favale A, Siracusa G (2001) Mesenchymal cell precursors of peritubular smooth muscle cells of the mouse testis can be identified by the presence of the p75 neurotrophin receptor. Biol Reprod 64(2):464-472. doi: 10.1095/biolreprod64.2.464 PMID: 11159348
Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)
Acetylcholine receptor-reactive antibody induces nitric oxide production by a rat skeletal muscle cell line: influence of cytokine environment.
Garcia YR, May JJ, Green AM, Krolick KA (2001) Acetylcholine receptor-reactive antibody induces nitric oxide production by a rat skeletal muscle cell line: influence of cytokine environment. J Neuroimmunol 120(1-2):103-111. doi: 10.1016/s0165-5728(01)00414-3 PMID: 11694325
Related Products: Nicotinic Acetylcholine Receptor alpha 1 (mAb 35) Rat Monoclonal (Cat. #AB-N36)
Localization of glutamate in the nervous system of the fly drosophila melanogaster: An immunocytochemical study
Sinakevitch-Pean I, Geffard M, Plotnikova SI (2001) Localization of glutamate in the nervous system of the fly drosophila melanogaster: An immunocytochemical study. Zh Evol Biokhim Fiziol 37(1):64-68. doi: 10.1023/A:1017574120553 PMID: 11424530
Related Products: L-Glutamate Rabbit Polyclonal, Conjugated (Cat. #AB-T08)
Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor.
Tierney ML, Unwin N (2000) Electron microscopic evidence for the assembly of soluble pentameric extracellular domains of the nicotinic acetylcholine receptor. J Mol Biol 303(2):185-196. doi: 10.1006/jmbi.2000.4137 PMID: 11023785
Related Products: Nicotinic Acetylcholine Receptor alpha 1 (mAb 35) Rat Monoclonal (Cat. #AB-N36)
Expression and channel properties of alpha-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons.
McNerney ME, Pardi D, Pugh PC, Nai Q, Margiotta JF (2000) Expression and channel properties of alpha-bungarotoxin-sensitive acetylcholine receptors on chick ciliary and choroid neurons. J Neurophysiol 84(3):1314-1329. doi: 10.1152/jn.2000.84.3.1314 PMID: 10980005
Related Products: Nicotinic Acetylcholine Receptor alpha 1 (mAb 35) Rat Monoclonal (Cat. #AB-N36)
Early migratory rat neural crest cells express functional gap junctions: Evidence that neural crest cell survival requires gap junction function.
Bannerman P, Nichols W, Puhalla S, Oliver T, Berman M, Pleasure D (2000) Early migratory rat neural crest cells express functional gap junctions: Evidence that neural crest cell survival requires gap junction function. J Neurosci Res 61:605-615. doi: 10.1002/1097-4547(20000915)61:6<605::AID-JNR4>3.0.CO;2-U PMID: 10972957
Summary: Gap junctions are vital for intercellular communication, especially during development. Neural crest cells develop into several types of neural cells, often migrating as a mass of cells to their final destinations. Bannerman et al. use the anti-p75 antibody (Cat. #AB-N01) to confirm the presence of p75 in neural crest cells. The authors examine how crucial survival signals are communicated during migration and demonstrate that interfering with gap junction formation causes death of neural crest cells.
Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)
Identification of a human olfactory ensheathing cell that can effect transplant mediated remyelination of demyelinated CNS axons.
Barnett SC, Alexander CL Iwashita Y, Gilson JM, Crowther J, Clark L, Dunn KT, Papanastassiou V, Kennedy PG, Franklin RJ (2000) Identification of a human olfactory ensheathing cell that can effect transplant mediated remyelination of demyelinated CNS axons. Brain 123:1581-1588. doi: 10.1093/brain/123.8.1581 PMID: 10908188
Related Products: NGFr (mu p75) Rabbit Polyclonal (Cat. #AB-N01)