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Structure and biological properties of ribosome-inactivating proteins and lectins from elder (Sambucus nigra L.) leaves

Iglesias R, Russo R, Landi N, Valletta M, Chambery A, Di Maro A, Bolognesi A, Ferreras JM, Citores L (2022) Structure and biological properties of ribosome-inactivating proteins and lectins from elder (Sambucus nigra L.) leaves. Toxins 14(9):611. doi: 10.3390/toxins14090611

Summary: This work contributes to expanding our knowledge of the family of RIPs and RIP-related lectins produced by Sambucus nigra, with eight new proteins found in leaves: one type 2 RIP and two related lectins that are specific for galactose, four type 2 RIPs with deficient sugar binding domains and one type 1 RIP. This knowledge is important for the potential medical and biotechnological use of these proteins.

Other Information: 3CA5: Sambucus nigra agglutinin II (SNA-II)-tetragonal crystal form-complexed to alpha1 methylgalactose

https://www.rcsb.org/3d-view/3CA5/1

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