Haddad G, Zhu LF, Rayner DC, Murray AG ( 2013 ) Experimental glomerular endothelial injury in vivo. PLoS One 8(10):e78244 . doi: 10.1371/journal.pone.0078244 Related Products: MOA-SAP (Cat. #IT-92)
Experimental glomerular endothelial injury in vivo. Read More »
Wiater MF, Li AJ, Dinh TT, Jansen HT, Ritter S (2013) Leptin-sensitive neurons in the arcuate nucleus integrate activity and temperature circadian rhythms and anticipatory responses to food restriction. Am J Physiol Regul Integr Comp Physiol 305(8):R949-R960. doi: 10.1152/ajpregu.00032.2013 Summary: The arcuate nucleus (Arc) of the hypothalamus is known to participate in the regulation of
Khasabov SG, Simone DA (2013) Loss of neurons in rostral ventromedial medulla that express neurokinin-1 receptors decreases the development of hyperalgesia. Neuroscience 250C:151-165. doi: 10.1016/j.neuroscience.2013.06.057 Summary: Previous data has indicated that neurokinin-1 receptors are located on ON cells in the rostral ventromedial medulla (RVM). ON cells are considered pronociceptive because noxious stimulation is stimulatory. In
Parent MJ, Cyr M, Aliaga A, Kostikov A, Schirrmacher E, Soucy JP, Mechawar N, Rosa-Neto P, Bedard MA (2013) Concordance between in vivo and postmortem measurements of cholinergic denervation in rats using PET with [18F]FEOBV and choline acetyltransferase immunochemistry. EJNMMI Res 3(1):70. doi: 10.1186/2191-219X-3-70 Summary: Positron emission tomography (PET) imaging agents have been developed for
Screening large numbers of antibodies for the ability to internalize can be prohibitively expensive in both cost and time. The ZAP Antibody Internalization Kit contains all the components needed for three 96-well plates, or 288 tests. The ability to perform a diagnostic screen that is amenable to high-throughput methods, prior to direct conjugation of those
Targeting Tools: ZAP Antibody Internalization Kit Read More »
Q: We have a publication in review and put this statement in the paper, “The mouse monoclonal antibody to the low affinity nerve growth factor receptor (p75NTR; Advanced Targeting Systems) was derived from immunization of mice with WM245 melanoma cells and recognizes p75NTR in human, primate, rabbit, sheep, dog, cat, and pig. According to the
Flow cytometry for AB-N07 Read More »
Baxter MG, Bucci DJ, Gorman LK, Wiley RG, Gallagher M (2013) Reprint: Selective immunotoxic lesions of basal forebrain cholinergic cells: Effects on learning and memory in rats. Behav Neurosci 127(5):619-627 . doi: 10.1037/a0033939 Summary: In this reprint of a 1995 article, 192-IgG-SAP (Cat. #IT-01) was used to separate the depletion of cortical cholineacetyltransferase and behavioral
Baxter MG, Bucci DJ (2013) Selective immunotoxic lesions of basal forebrain cholinergic neurons: twenty years of research and new directions. Behav Neurosci 127(5):611-618 . doi: 10.1037/a0033781 Summary: This review covers twenty years of basal forebrain cholinergic lesioning. The initial use of 192-IgG-SAP (Cat. #IT-01) is discussed, as well as other immunotoxins such as GAT-1-SAP (Cat.
Ferrini F, De Koninck Y (2013) Featured Article: Role of spinal microglia in the development of morphine-induced hyperalgesia. Targeting Trends 14(4) Related Products: Mac-1-SAP rat (Cat. #IT-33), Saporin (Cat. #PR-01) Read the featured article in Targeting Trends. See Also: Ferrini F et al. Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl(-) homeostasis. Nat Neurosci