Chlorotoxin-SAP [IT-86]


SKU: IT-86 Category: Product Size: 25 ug, 100 ug, 250 ug, 1 mg | Conjugate: streptavidin-saporin | Usage: eliminates cells |

Chlorotoxin is a 36 amino acid peptide that comes from the venom of the deathstalker scorpion (Leiurus quinquestriatus). Chlorotoxin targets cells expressing matrix metalloproteinase-2 isoforms. These isoforms are specifically upregulated in gliomas and other cancers of neuroectodermal origin, but are not normally expressed in the brain. Chlorotoxin is a high-affinity peptide ligand for chloride channels in glioma cells, but does not affect normal glial cells.

Chlorotoxin-SAP eliminates cells expressing MMP-2 isoforms.

View Data Sheet

View References

You may also like…