Oxytocin is a nine amino acid peptide with a structure similar to vasopressin, and is a hormone released by the posterior pituitary. Peripheral activity of oxytocin is linked primarily to lactation and labor-related uterine contractions. Within the brain, oxytocin receptor-positive neurons have been studied with regard to their sensitivity to leptin and involvement in satiety.
Oxytocin-SAP is a chemical conjugate of native oxytocin peptide and the ribosome-inactivating protein, saporin. It specifically eliminates cells that recognize and internalize oxytocin in rat and mouse.
Oxytocin-SAP is available individually (Cat. #IT-46) or as a kit (Cat. #KIT-46) which includes Oxytocin-SAP and Blank-SAP (Cat. #IT-21).
keywords: oxytocin, saporin, Somatostatin-positive interneurons, pyramidal neurons, hippocampus, neocortex, mossy cells, dentate gyrus
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