Frizzled proteins are a family of atypical G protein-coupled receptors involved in several critical signaling pathways, most notably the Wnt pathway. These receptors are essential in both developing and mature organisms, where they regulate key biological processes such as cell polarity, embryonic patterning, neural synapse formation, and cell proliferation. In Drosophila, the frizzled (fz) gene plays a central role in coordinating epidermal cell cytoskeletons, leading to the orderly alignment of cuticular hairs and bristles.
This IgG1 antibody was generated against amino acids 1-252 of Drosophila melanogaster frizzled protein.
Applications include western blot and immunofluorescence.
