BoNT/E Rabbit Polyclonal [AB-44]


SKU: AB-44 Category: Quantity: 100 ul | Antibody Type: Polyclonal | Host: Rabbit | Conjugate: unconjugated | Usage: ELISA, immunoblotting |

Clostridium botulinum is a Gram-positive bacterium that produces neurotoxins; A through G. Botulinum neurotoxins (BoNTs) induce paralysis of peripheral neurons by inhibiting the formation of neurotransmitter-carrying vesicles to the plasma membrane. Botulinum toxin type E (BoNT/E) is a zinc protease responsible for cleavage of synaptosomal-associated protein 25 (SNAP25) between residues 180 and 181, consequently inhibiting the formation of synaptic vesicles.

This antibody recognizes catalytic light chain of Botulinum toxin type E (BoNT/E). The light chain (Lc) of BoNT/E has a molecular weight of 50 kDa. Recombinant BoNT/E was used as the immunogen. It is routinely tested by ELISA and western blot.

Applications include ELISA and immunoblotting.

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