Corticotropin Releasing Hormone Rabbit Polyclonal [AB-02]

Name: Corticotropin Releasing Hormone Rabbit Polyclonal [AB-02]
SKU: AB-02
Availability: InStock

$475.00

Corticotropin-releasing hormone/factor (CRH/CRF) is the principal neuropeptide involved in regulating the stress response. It stimulates ACTH release from the pituitary gland. When centrally administered to animals it produces somatic changes analogous to those seen in both depression and anxiety. In humans, it is capable of reproducing the hormonal changes which are characteristically seen in depressed patients.

This antibody recognizes human and rat corticotropin-releasing hormone/factor. The immunogen was raised in rabbits against the synthetic fragment of rat CRF (1-41). The antibody is routinely tested by dot blot.

Applications include radioimmunoassay, affinity chromatography, immunoblotting, immunostaining and immunocytochemistry.

keywords: CRH, CRF, corticotropin releasing hormone, corticotropin releasing factor, CHRH, Anti-CRH, Anti-CRF, Anti-Corticotropin Releasing Hormone

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Effects of crowding stress on the hypothalamo-pituitary-interrenal axis of the self-fertilizing fish, Kryptolebias marmoratus

Amano M, Amiya N, Fukushima K, Hagio H, Yamamoto N, Sakakura Y (2022) Effects of crowding stress on the hypothalamo-pituitary-interrenal axis of the self-fertilizing fish, Kryptolebias marmoratus. Comp Biochem Physiol A Mol Integr Physiol 264:111110. doi: 10.1016/j.cbpa.2021.111110 PMID: 34737084

Objective: To test whether crowding stress affects the hypothalamo-pituitary-interrenal (HPI) axis of the self-fertilizing fish, Kryptolebias marmoratus.

Summary: The number of CRH-ir cell bodies and cortisol levels were significantly higher in paired fish. The results indicate that crowding stress affects the HPI axis in K. marmoratus which thrive in small burrows with limited water volume.

Usage: Immunohistochemistry (1:2000)

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Disrupted compensatory response mediated by Wolfram syndrome 1 protein and corticotrophin-releasing hormone family peptides in early-onset intrahepatic cholestasis pregnancy

Xu T, Zhou Z, Liu N, Deng C, Huang G, Zhou F, Liu X, Wang X (2019) Disrupted compensatory response mediated by Wolfram syndrome 1 protein and corticotrophin-releasing hormone family peptides in early-onset intrahepatic cholestasis pregnancy. Placenta 83:63-71. doi: 10.1016/j.placenta.2019.06.378 PMID: 31477210

Usage: Western (1:1000)

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Effects of Shugan Hewei Granule on depressive behavior and protein expression related to visceral sensitivity in a rat model of nonerosive reflux disease.

Wang Y, Li G, Wang X, Zhu S (2019) Effects of Shugan Hewei Granule on depressive behavior and protein expression related to visceral sensitivity in a rat model of nonerosive reflux disease. Evid Based Complement Alternat Med 2019:1505693. doi: 10.1155/2019/1505693 PMID: 30719054

Usage: immunofluorescent staining (1:200)

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