Targeting Trends Newsletter 14q2

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Newsletter Highlights

  • 20 Years of Special People (page 2)
  • Top 20 Teaser Winners (page 2)
  • 20 Most-Cited References (page 3)
  • Top Q&A (page 5)
  • Complete and Submit the Targeting Teaser online!

Celebrating Twenty Years of Science Advanced Targeting Systems (founded 22 Apr 1994)

Product information related to cover article: 192-IgG-SAP, SP-SAP, Bombesin-SAP

Celebrating Twenty Years of People Who Make ATS Special

Targeting Teaser Solution and Winners plus Top Twenty All-Time Winners

Top Twenty Most-Cited References

Recent Scientific References (read summaries)

  • Ogawa S, Nathan FM, Parhar IS. (2014) Habenular kisspeptin modulates fear in the zebrafish. Proc Natl Acad Sci U S A 111(10):3841-3846. (Cat. #IT-21)
  • Yin S, Noetzel MJ, Johnson KA, Zamorano R, Jalan-Sakrikar N, Gregory KJ, Conn PJ, Niswender CM. (2014) Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS. J Neurosci 34(1):79-94. (Cat. #AB-N32)
  • Roland JJ, Stewart AL, Janke KL, Gielow MR, Kostek JA, Savage LM, Servatius RJ, Pang KC. (2014) Medial septum-diagonal band of Broca (MSDB) GABAergic regulation of hippocampal acetylcholine efflux is dependent on cognitive demands. J Neurosci 34(2):506-514. (Cat. #IT-32)
  • Ljubojevic V, Luu P, De Rosa E. (2014) Cholinergic contributions to supramodal attentional processes in rats. J Neurosci 34(6):2264-2275. (Cat. #IT-01)
  • Quadros EV, Nakayama Y, Sequeira JM. (2013) Saporin Conjugated Monoclonal Antibody to the Transcobalamin Receptor TCblR/320 Is Effective in Targeting and Destroying Cancer Cells. J Cancer Ther 4(6):1074-1081. (Custom Conjugate)
  • Douglas AD, Williams AR, Knuepfer E, Illingworth JJ, Furze JM, Crosnier C, Choudhary P, Bustamante LY, Zakutansky SE, Awuah DK, Alanine DG, Theron M, Worth A, Shimkets R, Rayner JC, Holder AA, Wright GJ, Draper SJ. (2014) Neutralization of Plasmodium falciparum Merozoites by Antibodies against PfRH5. J Immunol 192(1):245-258. (Cat. #AB-42)
  • Lund K, Bostad M, Skarpen E, Braunagel M, Krauss S, Duncan A, Hogset A, Selbo P. (2014) The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines. MAbs 6(3)(Cat. #IT-27)
  • Lee SC, Seo KW, Kim HJ, Kang SW, Choi HJ, Kim A, Kwon BS, Cho HR, Kwon B. (2015) Depletion of Alloreactive T-Cells by Anti-CD137-Saporin Immunotoxin. Cell Transplant 24(6):1167-1181. PMID: 24594433 (Cat. #IT-35)
  • Cutuli D, De Bartolo P, Caporali P, Tartaglione AM, Oddi D, D’Amato FR, Nobili A, D’Amelio M, Petrosini L. (2013) Neuroprotective effects of donepezil against cholinergic depletion. Alzheimers Res Ther 5(5):50. (Cat. #IT-01)
  • Suto T, Severino AL, Eisenach JC, Hayashida KI. (2014) Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms. Neuropharmacology 81C:95-100. (Cat. #IT-03, Cat. #IT-18)
  • Li AJ, Wang Q, Dinh TT, Powers BR, Ritter S. (2014) Stimulation of feeding by three different glucose-sensing mechanisms requires hindbrain catecholamine neurons. Am J Physiol Regul Integr Comp Physiol 306(4):R257-64. (Cat. #IT-03, Cat. #PR-01)
  • Weisshaar CL, Winkelstein BA. (2014) Ablating Spinal NK1-Bearing Neurons Eliminates the Development of Pain and Reduces Spinal Neuronal Hyperexcitability and Inflammation From Mechanical Joint Injury in the Rat. J Pain 15(4):378-386 (Cat. #IT-11, Cat. #IT-21)
  • Watanabe T, Ito T, Inoue G, Ohtori S, Kitajo K, Doya H, Takahashi K, Yamashita T. (2008) The p75 receptor is associated with inflammatory thermal hypersensitivity. J Neurosci Res 86(16):3566-3574. (Cat. #AB-N01)
  • Takakura AC, Barna BF, Cruz JC, Colombari E, Moreira TS. (2014) Phox2b-expressing retrotrapezoid neurons and the integration of central and peripheral chemosensory control of breathing in conscious rats. Exp Physiol 99(3):571-585. (Cat. #IT-11)
  • Ye Y, Bae S, Viet CT, Troob S, Bernabe D, Schmidt BL. (2014) IB4(+) and TRPV1(+) sensory neurons mediate pain but not proliferation in a mouse model of squamous cell carcinoma. Behav Brain Funct 10(1):5. (Cat. #IT-10, Cat #PR-01)
  • Cordier D, Sailer M, Gerber A, Kluba C, Bauman A, Hutter G, Mindt TL, Mariani L. (2014) Expression of Different Neurokinin-1 Receptor (NK1R) Isoforms in Glioblastoma Multiforme: Potential Implications for Targeted Therapy. Cancer Biother Radiopharm Epub(Cat. #IT-11)

Targeting Talk: Top Q & A

Upcoming Events

  • FENS / July 5-9, 2014/ Milan, Italy / Booth #25
  • SFN / November 15-19, 2014 / Washington, DC / Booth #1019

Recent Scientific References (continued, read summaries)

Targeting Stars: SFN Poster Winners

Targeting Tools: Top Twenty (Five Each in Four Categories)

  • Targeted Toxins
  • Secondary Conjugates
  • Antibodies
  • Publications

Targeting Technology Tutorial

Targeting Teaser (Jumble) – Win a ATS 20th Anniversary Tote Bag!