Targeting Trends Newsletter 13q4

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Newsletter Highlights

  • Spring Brain Conference 25th Anniversary (page 2)
  • Targeting Talk: Antibody questions…answered (page 5)
  • ZAP Antibody Internalization Kit (page 7)
  • Complete and Submit the Targeting Teaser online!

Role of spinal microglia in the development of morphine-induced hyperalgesia
(continued on page 6)

Contributed by Francesco Ferrini1 and Yves De Koninck2,3
1) Department of Veterinary Sciences, University of Turin,10095 Grugliasco, Turin, Italy

2) Institut universitaire en santé mentale de Québec, QC, G1J 2G3, Canada

3) Department of Psychiatry and Neuroscience, Université Laval, Québec, QC, G13 7P4, Canada

Product information related to cover article: Mac-1-SAP (Cat. #IT-33) and Saporin (Cat. #PR-01)


Spring Brain Conference 25th Anniversary
Come to the SBC Anniversary Social in San Diego, Nov 10 5-7pm

Congratulations Newlyweds: Mr. & Mrs. Brian Russell


Recent Scientific References (read summaries)

  • Lee YS, Danandeh A, Baratta J, Lin CY, Yu J, Robertson RT. (2013) Neurotrophic factors rescue basal forebrain cholinergic neurons and improve performance on a spatial learning test. Exp Neurol 249C:178-186. (Cat. #IT-01)
  • Ovsepian SV, Antyborzec I, O’Leary VB, Zaborszky L, Herms J, Oliver Dolly J. (2013) Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Abeta) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons. Brain Struct Funct Epub(Cat. #FL-01)
  • Wenker IC, Sobrinho CR, Takakura AC, Mulkey DK, Moreira TS. (2013) P2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure. Hypertension 62(2):263-273. (Cat. #IT-03)
  • Keimpema E, Zheng K, Barde SS, Berghuis P, Dobszay MB, Schnell R, Mulder J, Luiten PG, Xu ZD, Runesson J, Langel U, Lu B, Hokfelt T, Harkany T. (2013) GABAergic Terminals Are a Source of Galanin to Modulate Cholinergic Neuron Development in the Neonatal Forebrain. Cereb Cortex Epub(Cat. #IT-34)
  • Tai SK, Ma J, Leung LS. (2013) Medial Septal Cholinergic Neurons Modulate Isoflurane Anesthesia. Anesthesiology Epub(Cat. #IT-01)
  • Neace CJ, Alderete JF. (2013) Epitopes of the Highly Immunogenic Trichomonas vaginalis alpha-Actinin Are Serodiagnostic Targets for Both Women and Men. J Clin Microbiol 51(8):2483-2490. (Cat. #AB-213)
  • Wiater MF, Li AJ, Dinh TT, Jansen HT, Ritter S. (2013) Leptin-sensitive neurons in the arcuate nucleus integrate activity and temperature circadian rhythms and anticipatory responses to food restriction. Am J Physiol Regul Integr Comp Physiol 305(8):R949-R960. (Cat. #IT-47, Cat. #IT-21)
  • Guyenet PG, Stornetta RL, Bochorishvili G, Depuy SD, Burke PG, Abbott SB. (2013) C1 neurons: the body’s EMTs. Am J Physiol Regul Integr Comp Physiol 305(3):R187-204. (Cat. #IT-03)
  • Khasabov SG, Simone DA. (2013) Loss of neurons in rostral ventromedial medulla that express neurokinin-1 receptors decreases the development of hyperalgesia. Neuroscience 250C:151-165. (Cat. #IT-11, Cat. #IT-21)
  • Baxter MG, Bucci DJ. (2013) Selective Immunotoxic Lesions of Basal Forebrain Cholinergic Neurons: Twenty Years of Research and New Directions. Behav Neurosci Epub(Cat. #IT-01, Cat. #IT-02, Cat. #IT-32)
  • Gulino R, Gulisano M. (2013) Noggin and Sonic hedgehog are involved in compensatory changes within the motoneuron-depleted mouse spinal cord. J Neurol Sci 332(1-2):102-109. (Cat. #IT-14)
  • Gelfo F, Petrosini L, Graziano A, De Bartolo P, Burello L, Vitale E, Polverino A, Iuliano A, Sorrentino G, Mandolesi L. (2013) Cortical Metabolic Deficits in a Rat Model of Cholinergic Basal Forebrain Degeneration. Neurochem Res 38(10):2114-2123. (Cat. #IT-01)
  • Chang ST, Liu YP, Huang CL, Wang PY, Tung CS. (2013) Implication of Cerebral Dopamine-beta Hydroxylase for Cardiovascular and Mood Regulation in Rats. Chin J Physiol 56(4)(Cat. #IT-03, Cat. #PR-01)


Role of spinal microglia in the development of morphine-induced hyperalgesia
(continued from page 1)

Upcoming Events

  • Society for Neuroscience / November 10-13, 2013 / San Diego, CA / Booth #1120
  • American Association for Cancer Research / April 5-9, 2014/
    San Diego, CA

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