Targeting Trends Newsletter 09q4

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Newsletter Highlights

  • 2009 SfN Posters (page 2)
  • Anti-Melanopsin Protocol Correction (page 5)
  • Teaser Winners (page 5)
  • New Products: Leptin-SAP, Oxytocin-SAP, Anti-Basigin (page 7)
  • Complete and Submit the Targeting Teaser online!

Ablation of GRPR+ Neurons in the Spinal Cord by Bombesin-Saporin Knocks Out Itch Sensation in Mice Without Affecting Pain Circuit – read article (continued on page 6)

Contributed by Zhou-Feng Chen, Yang-Gang Sun, Zhong-Qiu Zhao, Xiu-Li Meng, Jun Yin, Xian-Yu Liu Washington University Pain Center School of Medicine, Dept of Anesthesiology, St. Louis, MO 63141 Product information related to cover article: Bombesin-SAP (Cat. #IT-40) and Blank-SAP (Cat. #IT-21)

Recent Scientific References – read online

  • Zhu J, Xu W, Wang J, Ali SF, Angulo JA (2009) The Neurokinin-1 Receptor Modulates the Methamphetamine-Induced Striatal Apoptosis and Nitric Oxide Formation in Mice. J Neurochem [Epub Aug 13]. (Cat. #IT-11; Cat. #IT-01)
  • Zhang L, Moffatt-Bruce SD, Gaughan AA, Wang JJ, Rajab A, Hadley GA (2009) An anti-CD103 immunotoxin promotes long-term survival of pancreatic islet allografts. Am J Transplant 9:2012-2023. (Cat. #IT-18)
  • Vetrivelan R, Fuller PM, Tong Q, Lu J (2009) Medullary circuitry regulating rapid eye movement sleep and motor atonia. J Neurosci 29:9361-9369. (Cat. #IT-20)
  • Kaur S, Thankachan S, Begum S, Liu M, Blanco-Centurion C, Shiromani PJ (2009) Hypocretin-2 saporin lesions of the ventrolateral periaquaductal gray (vlPAG) increase REM sleep in hypocretin knockout mice. PLoS One 4:e6346. (Cat. #IT-20)
  • Ho NF, Han SP, Dawe GS (2009) Effect of voluntary running on adult hippocampal neurogenesis in cholinergic lesioned mice. BMC Neurosci 10:57. (Cat. #IT-16)
  • Fargo KN, Foster AM, Sengelaub DR (2009) Neuroprotective effect of testosterone treatment on motoneuron recruitment following the death of nearby motoneurons. Dev Neurobiol 69:825-835. (Cat. #IT-14)
  • Esclassan F, Coutureau E, Di Scala G, Marchand AR (2009) A cholinergic-dependent role for the entorhinal cortex in trace fear conditioning. J Neurosci 29:8087-8093. (Cat. #IT-01)
  • De Bartolo P, Gelfo F, Mandolesi L, Foti F, Cutuli D, Petrosini L (2009) Effects of chronic donepezil treatment and cholinergic deafferentation on parietal pyramidal neuron morphology. J Alzheimers Dis 17:177-191. (Cat. #IT-01)
  • Conner JM, Franks KM, Titterness AK, Russell K, Merrill DA, Christie BR, Sejnowski TJ, Tuszynski MH (2009) NGF is essential for hippocampal plasticity and learning. J Neurosci 29:10883-10889. (Cat. #IT-01)
  • Cao F, Chen SS, Yan XF, Xiao XP, Liu XJ, Yang SB, Xu AJ, Gao F, Yang H, Chen ZJ, Tian YK (2009) Evaluation of side effects through selective ablation of the mu opioid receptor expressing descending nociceptive facilitatory neurons in the rostral ventromedial medulla with dermorphin-saporin. Neurotoxicology [Epub Jun 24]. (Cat. #IT-12; Cat. #IT-01)
  • Aztiria E, Cataudella T, Spampinato S, Leanza G (2009) Septal grafts restore cognitive abilities and amyloid precursor protein metabolism. Neurobiol Aging 30:1614-1625. (Cat. #IT-01)
  • Sun YG, Zhao ZQ, Meng XL, Yin J, Liu XY, Chen ZF (2009) Cellular Basis of Itch Sensation. Science 325:1531-1534. (Cat. #IT-40)
  • Penaloza-MacMaster P, Masopust D, Ahmed R (2009) T-cell reconstitution without T-cell immunopathology in two models of T-cell-mediated tissue destruction. Immunology 128:164-171. (Cat. #IT-27)
  • Montero M, Gonzalez B, Zimmer J (2009) Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration. Brain Res 1291:140-152. (Cat. #IT-06)
  • Ma J, Tai SK, Leung LS (2009) Ketamine-induced deficit of auditory gating in the hippocampus of rats is alleviated by medial septal inactivation and antipsychotic drugs. Psychopharmacology (Berl) 206:457-467. (Cat. #IT-01)
  • Lopez-Aranda MF, Lopez-Tellez JF, Navarro-Lobato I, Masmudi-Martin M, Gutierrez A, Khan ZU (2009) Role of layer 6 of V2 visual cortex in object-recognition memory. Science 325:87-89. (Cat. #IT-02)
  • Dashniani MG, Beseliia GV, Maglakelidze GA, Burdzhanadze MA, Chkhikvishvili N (2009) Effects of the selective lesions of cholinergic septohippocampal neurons on different forms of memory and learning process. Georgian Med News 81-85. (Cat. #IT-01; Cat. #IT-18)
  • Aisa B, Gil-Bea FJ, Marcos B, Tordera R, Lasheras B, Del Rio J, Ramirez MJ (2009) Neonatal stress affects vulnerability of cholinergic neurons and cognition in the rat: Involvement of the HPA axis. Psychoneuroendocrinology [Epub Jun 6]. (Cat. #IT-01)

Targeting Talk (see text)

Upcoming Events

  • Society for Neuroscience, Booth #619 – Chicago, IL- October 17-21, 2009
  • American Society for Cell Biology – December 5-9, 2009 – San Diego, CA
  • American Association for Cancer Research – April 17-21, 2010 – Washington, DC

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