Targeting Trends Newsletter 04q3

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Newsletter Highlights

  • SP-SAP update (page 2)
  • Venice Watercolor (page 2)
  • Golf at Torrey Pines (page 6)
  • Acetylated LDL-SAP, FITC-labeled second antibodies (page 7)

The Discovery of Saporin – read article (continued on page 6)

Contributed by Dr. Fiorenzo Stirpe, Dipartimento di Patologia sperimentale, Università di Bologna, I-40125 Bologna, Italy

Product information related to cover article: Saporin (Cat. #PR-01)

SAP Facts

Drug Development Update – read article

Accomplished Scientist. . . Talented Artist – Rosalind Ridley

  • Doorway of Campo Sant’Angelo

Recent Scientific References – read online

Targeting Talk: Eliminating CBF Neurons – read online

  • What dosage of 192-Saporin should be used in the lateral ventricle to eliminate cholinergic neurons in the basal forebrain, including substantia innominata (SI)? I read that Calza et al (1) used 2 or 3 micrograms/4.5 ul and found this was highly effective.
  • Should we expect to be able to kill all or almost all ChAT SI neurons?
  • Is there another toxin that will eliminate the remaining ChAT SI neurons?

Upcoming Events

Targeting Teaser Solution and Winners

The Discovery of Saporin – read article (continued from page 1)

Golf Torrey Pines this October! (CANCELLED)

Targeting Tools: Featured Products

Targeting Technology Tutorial

Targeting Teaser (Jumble)