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- Funding Awarded (page 2)
- Retrograde Transport (page 5)
- Avidinylated-SAP (page 7)
Biotinylated targeting: A viable option? (continued on page 6)
For the IB4-SAP illustration (Figure 1), our thanks to Christopher N. Honda, Ph.D., Associate Professor, Department of Neuroscience, University of Minnesota, 6-145 Jackson Hall, 321 Church Street, Minneapolis, MN 55455
Malia and Sam Kohls: Has it been a YEAR already?
- I’m interested in using SAP to eliminate cells through retrograde transport, like OX7-SAP and IB4-SAP have been used. Can you explain how retrograde transport works and if it is possible for this to work with dermorphin-SAP? What determines whether a targeted toxin will be able to be used in retrograde transport?
- If a targeted toxin cannot be used in retrograde transport, will it only kill cell bodies in the injection site or will it also kill terminals?
Targeting Teaser Winners from last issue
Targeting Teaser (Jumble)