Anti-SERT-SAP References

Cat #IT-23

2019

Bernabe C, Caliman I, de Abreu A, Dustrude E, Molosh A, Shekhar A, & Johnson P. S38. Dissecting the Functional Heterogeneity of Serotonergic Systems That Regulate Fear and Panic. (2019). Biol Psychiatry, 85 (10):S311.

Objective:  To elucidate the role of these serotonergic networks on learned fear and innate panic responses.
Summary: LED excitation or lesioning of PeF projecting 5-HT system respectively attenuated and enhanced panic-associated escape/flight behaviors and cardioexcitation following a 7.5 and 20% CO2 challenge.
Dose:  Anti-SERT-SAP was injected  into the BLA or PeF to lesion these 5-HT pathways.

2018

Holschbach MA, Vitale EV, & Lonstein JS. Serotonin-specific lesions of the dorsal raphe disrupt maternal aggression and caregiving in postpartum rats. (2018). Behav Brain Res, 348 53-64.

KIT-23:  Anti-SERT-SAP, Mouse IgG-SAP
Objective:  To determine the effects of behavioral modifications associated with early motherhood by permanently disrupting serotonin signaling at one of its primary sources, the dorsal raphe (DR).
Summary:  Prepartum serotonin-specific lesions of the DRdm impaired maternal aggression.  Larger postpartum DR serotonin lesions affected both aggression and caregiving.  DR serotonin lesions did not affect postpartum anxiety,
Dose:  1 μL of 0.1M anti-SERT-SAP or control Mouse IgG-SAP was slowly infused into the DR.

2016

Bernabe CS, Caliman IF, Abreu ARR, Shekhar A, Johnson PL (2016) A unique subdivision of serotonergic neurons in the dorsal raphe nucleus projects to the basolateral amygdala complex to enhance fear-conditioned behaviors. Soc Neurosci Meeting Abstract 74.23

Vitale EM, Holschbach MA, Lonstein JS (2016) Maternal aggression is impaired by prepartum serotonin-specific lesions of the midbrain dorsal raphe. Soc Neurosci Meeting Abstract 338.01

2009

Nattie E, Li A (2009) Central chemoreception is a complex system function that involves multiple brain stem sites. J Appl Physiol 106:1464-1466. (Targeting Trends 09q3)

2008

See also: Society for Neuroscience 2008 Abstracts

2007

Dias MB, Nucci TB, Margatho LO, Antunes-Rodrigues J, Gargaglioni LH, Branco LG (2007) Raphe Magnus Nucleus is involved in ventilatory but not hypothermic response to CO2. J Appl Physiol 103(5):1780-1788. (Targeting Trends 07q4)

Gravitt K, Marson L (2007) Effect of the destruction of cells containing the serotonin reuptake transporter on urethrogenital reflexes. J Sex Med 4:322-330; discussion 330-321. (Targeting Trends 07q3)

Shen FM, Wang J, Ni CR, Yu JG, Wang WZ, Su DF (2007) Ketanserin-induced baroreflex enhancement in spontaneously hypertensive rats depends on central 5-HT(2A) receptors. Clin Exp Pharmacol Physiol 34:702-707. (Targeting Trends 07q4)

2006

Wiley RG. (2006) Targeted Toxins in Pain. Targeting Trends 7(2).

2005

See: Society for Neuroscience 2005 Abstracts

2004

Nattie EE, Li A, Richerson GB, Lappi DA (2004) Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556(1):235-253. (Targeting Trends 04q2)

See also: Society for Neuroscience 2004 Abstracts

2003

Feldman JL, Mitchell GS, Nattie EE (2003) Breathing: Rhythmicity, Plasticity, Chemosensitivity. Annu Rev Neurosci 26:239-266. (Targeting Trends 03q3)

See also: Society for Neuroscience 2003 Abstracts

2002

See also: Forum of European Neuroscience 2002 Abstracts and Society for Neuroscience 2002 Abstracts