2019
Bernabe C, Caliman I, de Abreu A, Dustrude E, Molosh A, Shekhar A, & Johnson P. S38. Dissecting the Functional Heterogeneity of Serotonergic Systems That Regulate Fear and Panic. (2019). Biol Psychiatry, 85 (10):S311.
Objective: To elucidate the role of these serotonergic networks on learned fear and innate panic responses.
Summary: LED excitation or lesioning of PeF projecting 5-HT system respectively attenuated and enhanced panic-associated escape/flight behaviors and cardioexcitation following a 7.5 and 20% CO2 challenge.
Dose: Anti-SERT-SAP was injected into the BLA or PeF to lesion these 5-HT pathways.
Pawluski JL, Li M, & Lonstein JS. Serotonin and motherhood: From molecules to mood. (2019). Front Neuroendocrinol, 53 100742. 2019/03/18. PMC6541513
Summary: Serotonin may affect how mothers perceive or behaviorally readjust to changes in the sensory cues emitted by their offspring as they age. The DR serotonin-lesioned mothers studied by Holschbach and colleagues (2018) were much less maternally aggressive, which was concomitant with reduced serotonin-immunoreactive fiber density in the anterior hypothalamus, a brain site previously implicated in serotonin’s influence on aggressive behaviors in male animals.
2018
Holschbach MA, Vitale EV, & Lonstein JS. Serotonin-specific lesions of the dorsal raphe disrupt maternal aggression and caregiving in postpartum rats. (2018). Behav Brain Res, 348 53-64.
KIT-23: Anti-SERT-SAP, Mouse IgG-SAP
Objective: To determine the effects of behavioral modifications associated with early motherhood by permanently disrupting serotonin signaling at one of its primary sources, the dorsal raphe (DR).
Summary: Prepartum serotonin-specific lesions of the DRdm impaired maternal aggression. Larger postpartum DR serotonin lesions affected both aggression and caregiving. DR serotonin lesions did not affect postpartum anxiety,
Dose: 1 μL of 0.1M anti-SERT-SAP or control Mouse IgG-SAP was slowly infused into the DR.
2016
Bernabe CS, Caliman IF, Abreu ARR, Shekhar A, Johnson PL (2016) A unique subdivision of serotonergic neurons in the dorsal raphe nucleus projects to the basolateral amygdala complex to enhance fear-conditioned behaviors. Soc Neurosci Meeting Abstract 74.23
Vitale EM, Holschbach MA, Lonstein JS (2016) Maternal aggression is impaired by prepartum serotonin-specific lesions of the midbrain dorsal raphe. Soc Neurosci Meeting Abstract 338.01
2009
Nattie E, Li A (2009) Central chemoreception is a complex system function that involves multiple brain stem sites. J Appl Physiol 106:1464-1466. (Targeting Trends 09q3)
2008
See also: Society for Neuroscience 2008 Abstracts
2007
Dias MB, Nucci TB, Margatho LO, Antunes-Rodrigues J, Gargaglioni LH, Branco LG (2007) Raphe Magnus Nucleus is involved in ventilatory but not hypothermic response to CO2. J Appl Physiol 103(5):1780-1788. (Targeting Trends 07q4)
Gravitt K, Marson L (2007) Effect of the destruction of cells containing the serotonin reuptake transporter on urethrogenital reflexes. J Sex Med 4:322-330; discussion 330-321. (Targeting Trends 07q3)
Shen FM, Wang J, Ni CR, Yu JG, Wang WZ, Su DF (2007) Ketanserin-induced baroreflex enhancement in spontaneously hypertensive rats depends on central 5-HT(2A) receptors. Clin Exp Pharmacol Physiol 34:702-707. (Targeting Trends 07q4)
2006
Wiley RG. (2006) Targeted Toxins in Pain. Targeting Trends 7(2).
2005
See: Society for Neuroscience 2005 Abstracts
2004
Nattie EE, Li A, Richerson GB, Lappi DA (2004) Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556(1):235-253. (Targeting Trends 04q2)
See also: Society for Neuroscience 2004 Abstracts
2003
Feldman JL, Mitchell GS, Nattie EE (2003) Breathing: Rhythmicity, Plasticity, Chemosensitivity. Annu Rev Neurosci 26:239-266. (Targeting Trends 03q3)
See also: Society for Neuroscience 2003 Abstracts
2002
See also: Forum of European Neuroscience 2002 Abstracts and Society for Neuroscience 2002 Abstracts