Cystatin C Rat Recombinant [PRP-438PRO]

Recombinant Rat Cystatin C

SKU: PRP-438PRO Categories: , Product Size: 2 ug, 10 ug, 1 mg | Host: E. coli | Conjugate: His-tag | Usage: immunoblotting |

Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C cause breakdown of the elastic laminae followed by atherosclerosis and abdominal aortic aneurysm.

Rat Cystatin C is a total of 134 AA with a calculated molecular weight of 14.93 kDa This recombinant protein was produced in E. coli and has an N-terminal His-tag (14AA). Purity is >96% as determined by SDS-PAGE.

Reported to be effective for immunoblotting (western blot).

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