CD-2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/bcm1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells. The cytoplasmic domain is associated with the signaling function.
Mouse anti-human CD2 (T11, LFA-2) is purified by ion exchange chromatography. The protein concentration is 1 mg/ml in PBS after reconstitution.
Reported to be effective as a blocking and staining antibody.
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