Dengue virus is caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. Each serotype is sufficiently different from the other such that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and in mice Morpholino antisense oligos have shown specific activity against dengue virus.
The monoclonal antibody to dengue virus envelope type 2 was purified by ion exchange column. The protein concentration is 1 mg/ml in PBS (after reconstitution). There is minimal cross-reactivity with other dengue subtypes.
Reported to be effective for intracellular staining of dengue-infected cells.
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