FabFc-ZAP rat Antibody Internalization Kit [KIT-88]

a tool to “piggyback” onto YOUR antibody via goat anti-rat monovalent antibody; targeting cells that recognize YOUR rat monoclonal antibody, eliminated via saporin

This kit includes FabFc-ZAP rat (Cat. #IT-88) plus Saporin (Cat. #PR-01) and Fab IgG-SAP (Cat. #IT-67) and reagents for developing a cytotoxicity assay.

SKU: KIT-88 Category: Product Size: 1 kit, tests 1 ab, 1 kit, tests 4 abs, 1 kit, tests 10 abs | Antibody Type: affinity-purified | Host: Goat | Reactivity: rat | Conjugate: saporin | Usage: eliminates cells, screen antibodies |
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FabFc-ZAP uses your primary rat monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. The secondary antibody used in the Fc-specific Fab-ZAP will react only with the Fc portion of the IgG heavy chain. The FabFc-ZAP products can be used in B-cell research with the confidence that cell death is primary antibody-mediated. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

FabFc-ZAP uses your rat primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

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View KIT-Z Secondary Antibody literature

View protocol(s) for this and other products

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