Chlorotoxin-SAP Kit [KIT-86]

chlorotoxin-saporin

SKU: KIT-86 Category: Product Size: 25 ug, 100 ug, 250 ug | Conjugate: streptavidin-saporin | Usage: eliminates cells |
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Chlorotoxin is a 36 amino acid peptide that comes from the venom of the deathstalker scorpion (Leiurus quinquestriatus). Chlorotoxin targets cells expressing matrix metalloproteinase-2 isoforms. These isoforms are specifically upregulated in gliomas and other cancers of neuroectodermal origin, but are not normally expressed in the brain. Chlorotoxin is a high-affinity peptide ligand for chloride channels in glioma cells, but does not affect normal glial cells.

Chlorotoxin-SAP eliminates cells expressing MMP-2 isoforms.

This kit includes Chlorotoxin-SAP (Cat. #IT-86) plus Blank-Streptavidin-ZAP (Cat. #IT-27B)

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