Anti-CD105-SAP Kit [KIT-80]

25 ug, 100 ug, 250 ug

anti-human CD105-saporin
This kit includes Anti-CD105-SAP (Cat. #IT-80) plus BIgG-SAP Mouse (Cat. #IT-74)

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SKU: KIT-80 Category:

Description

CD105 is also known as Endoglin and it modulates cellular response to TGF-β, involved in vascular development and remodeling. It is a type I integral membrane homodimer protein with subunits of 90 kD found on vascular endothelial cells, bone marrow stromal cells, and hematopoietic stem/progenitor cells. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on activated monocytes and tissue macrophages. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation. CD105 is a component of the TGF-β receptor system in human umbilical vein endothelial cells and binds TGF-β1 and β3 with high affinity but does not bind to TGF-β2.

Anti-CD105-SAP eliminates cells expressing human CD105 (Endoglin). All other cells are left untouched.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

View Anti-CD105-SAP Data Sheet
View BIgG-SAP Mouse Data Sheet

View Related Anti-CD105-SAP References

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