FabFc-ZAP human Antibody Internalization Kit [KIT-65]

1 kit, tests 1 ab, 1 kit, tests 4 abs, 1 kit, tests 10 abs

a tool to “piggyback” onto YOUR antibody via goat anti-human monovalent antibody; targeting cells that recognize YOUR human monoclonal antibody, eliminated via saporin
This kit includes FabFc-ZAP human (Cat. #IT-65) plus Saporin (Cat. #PR-01) and Fab IgG-SAP (Cat. #IT-67)

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SKU: KIT-65 Category:

Description

FabFc-ZAP uses your primary human monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. The secondary antibody used in the Fc-specific Fab-ZAP will react only with the Fc portion of the IgG heavy chain. The FabFc-ZAP products can be used in B-cell research with the confidence that cell death is primary antibody-mediated. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

FabFc-ZAP uses your human primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Three sizes are available; each kit includes assay reagents and the following aliquots of Fab-ZAP and control:

KIT-65-Z (tests 1 ab) includes 10 mcg each of FabFc-ZAP and Control Fab-IgG-SAP

KIT-65-Z4 (tests 4 abs) includes 40 mcg each of FabFc-ZAP and Control Fab-IgG-SAP

KIT-65-Z10 (tests 10 abs) includes 100 mcg each of FabFc-ZAP and Control Fab-IgG-SAP

View FabFc-ZAP human Data Sheet
View Saporin Data Sheet
View Fab IgG-SAP Data Sheet
View PMS Data Sheet
View XTT Data Sheet

View Related FabFc-ZAP human References
View Related Saporin References
View Related Fab IgG-SAP References

View ZAP video tutorials

View KIT-Z Secondary Antibody literature

View protocol(s) for this and other products

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