FabFc-ZAP uses your primary human monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. The secondary antibody used in the Fc-specific Fab-ZAP will react only with the Fc portion of the IgG heavy chain. The FabFc-ZAP products can be used in B-cell research with the confidence that cell death is primary antibody-mediated. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.
FabFc-ZAP uses your human primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.
Three sizes are available; each kit includes assay reagents and the following aliquots of Fab-ZAP and control:
KIT-65-Z (tests 1 ab) includes 10 mcg each of FabFc-ZAP and Control Fab-IgG-SAP
KIT-65-Z4 (tests 4 abs) includes 40 mcg each of FabFc-ZAP and Control Fab-IgG-SAP
KIT-65-Z10 (tests 10 abs) includes 100 mcg each of FabFc-ZAP and Control Fab-IgG-SAP