Fab-ZAP rat Antibody Internalization Kit [KIT-55]

1 kit, tests 1 ab, 1 kit, tests 4 abs, 1 kit, tests 10 abs

a tool to “piggyback” onto YOUR antibody via goat anti-rat monovalent antibody; targeting cells that recognize YOUR rat monoclonal antibody, eliminated via saporin
This kit includes Fab-ZAP rat (Cat. #IT-55) plus Saporin (Cat. #PR-01) and Fab IgG-SAP (Cat. #IT-67).

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SKU: KIT-55 Category:

Description

Fab-ZAP uses your primary rat monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. Fab-ZAP is made with a monovalent secondary antibody eliminating the possibility of cap formation, while preserving all the qualities that make an effective in vitro diagnostic tool. The antibodies used are affinity-purified polyclonal antibodies against both the heavy and light chain of rat IgG. The antibody used in this product will cross-react across immunoglobulin classes and subclasses of the same species as they share the same light chain (either kappa or lambda). It also has an improved EC50 when directly compared to Rat-ZAP in a cytotoxicity assay.

Fab-ZAP uses your rat primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Three sizes are available; each kit includes assay reagents and the following aliquots of Fab-ZAP and control:

KIT-55-Z (tests 1 ab) includes 10 mcg each of Fab-ZAP and Control Fab-IgG-SAP

KIT-55-Z4 (tests 4 abs) includes 40 mcg each of Fab-ZAP and Control Fab-IgG-SAP

KIT-55-Z10 (tests 10 abs) includes 100 mcg each of Fab-ZAP and Control Fab-IgG-SAP

View Fab-ZAP rat Data Sheet
View Saporin Data Sheet
View Fab IgG-SAP Data Sheet
View PMS Data Sheet
View XTT Data Sheet

View Related Fab-ZAP rat References
View Related Saporin References
View Related Fab IgG-SAP References

View ZAP video tutorials

View KIT-Z Secondary Antibody literature

View protocol(s) for this and other products

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