Hug-M-ZAP Antibody Internalization Kit [KIT-43]

1 kit, tests 1 ab, 1 kit, tests 4 abs, 1 kit, tests 10 abs

a tool to “piggyback” onto YOUR antibody via affinity-purified goat anti-human IgM; targeting cells that recognize YOUR primary human monoclonal IgM antibody, eliminated via saporin
This kit includes Hug-M-ZAP (Cat. #IT-43) plus Saporin (Cat. #PR-01) and Goat IgG-SAP (Cat. #IT-19)

Clear
SKU: KIT-43 Category:

Description

Hug-M-ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-human IgM) to “piggyback” onto YOUR human primary antibody. Hug-M-ZAP can be utilized for screening human IgM antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

Hug-M-ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.

Three sizes are available; each kit includes assay reagents and the following aliquots of Hug-M-ZAP and control:

KIT-43-Z (tests 1 ab) includes 25 mcg each of Hug-M-ZAP and Control Goat-IgG-SAP

KIT-43-Z4 (tests 4 abs) includes 100 mcg each of Hug-M-ZAP and Control Goat-IgG-SAP

KIT-43-Z10 (tests 10 abs) includes 250 mcg each of Hug-M-ZAP and Control Goat-IgG-SAP

View Hug-M-ZAP Data Sheet
View Saporin Data Sheet
View Goat IgG-SAP Data Sheet
View PMS Data Sheet
View XTT Data Sheet

View Related Hug-M-ZAP References
View Related Saporin References
View Related Goat IgG-SAP References

View ZAP video tutorials

View KIT-Z Secondary Antibody literature

View protocol(s) for this and other products

You may also like…