Hug-M-ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-human IgM) to “piggyback” onto YOUR human primary antibody. Hug-M-ZAP can be utilized for screening human IgM antibodies for internalization and/or their suitability to make potent immunotoxins. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.
Hug-M-ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.
Three sizes are available; each kit includes assay reagents and the following aliquots of Hug-M-ZAP and control:
KIT-43-Z (tests 1 ab) includes 25 mcg each of Hug-M-ZAP and Control Goat-IgG-SAP
KIT-43-Z4 (tests 4 abs) includes 100 mcg each of Hug-M-ZAP and Control Goat-IgG-SAP
KIT-43-Z10 (tests 10 abs) includes 250 mcg each of Hug-M-ZAP and Control Goat-IgG-SAP