Decreased serotonergic neurotransmission has been proposed to play a key role in the etiology of depression. Recent findings suggest that SERT might be linked to both neurotic and sexual behavior as well as to obsessive-compulsive disorder (OCD). Anti-SERT-SAP specifically eliminates cells expressing SERT making it an excellent tool for studying the sertonergic system which is known to modulate mood, emotion, sleep and appetite and thus is implicated in the control of numerous behavioral and physiological functions.
Anti-SERT-SAP specifically eliminates SERT-expressing cells in vitro and in vivo. All other cells are left untouched.
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