CTB-SAP Kit [KIT-14]

a tool for eliminating cells that express the GM1 receptor; targeted via cholera toxin B-subunit, eliminated via saporin
This kit includes CTB-SAP (Cat. #IT-14) plus Saporin (Cat. #PR-01)

SKU: KIT-14 Category: Product Size: 25 ug, 100 ug, 250 ug | Conjugate: saporin | Usage: eliminates cells |
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Description

IT-14

Cholera toxin B (CTB) binds the GM1 (Galactosyl-N-Acetylgalactosaminyl) receptor. This receptor is found on cells such as motoneurons, sympathetic pre-ganglionic neurons, as well as cells in the intestinal epithelium. CTB-SAP causes ablation of any cell type expressing GM1, including preganglionic neurons, motoneurons, and astrocytes. Intrathecal injection of CTB-SAP results in elimination of oligodendrocytes and astrocytes and the subsequent demyelination of the spinal cord. CTB-SAP allows the study of a number of demyelinating conditions.

Applications include ablation of any cell type expressing the GM1 receptor, including preganglionic neurons, motoneurons, and astrocytes.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

View CTB-SAP Data Sheet
View Saporin Data Sheet

View Related CTB-SAP References
View Related Saporin References

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