Acetylated LDL-SAP Kit [KIT-08]

a tool for eliminating cells that express microglia in primary cell cultures; targeted via acetylated human low density lipoprotein, eliminated via saporin
This kit includes Acetylated LDL-SAP (Cat. #IT-08) plus Saporin (Cat. #PR-01)

SKU: KIT-08 Category: Product Size: 25 ug, 100 ug, 250 ug | Host: Human | Reactivity: rat | Conjugate: saporin | Usage: eliminates cells |

Acetylated-LDL-Saporin (acLDL-SAP) has been used effectively to eliminate microglia from primary cultures of rat hippocampal neurons, while having no deleterious effect on neurons or astroglia. After 24 hours exposure, 3 åµg/ml of acLDL-SAP selectively kills more than 90% of microglia cells. acLDL-SAP is excellent for removing contaminating macrophages from primary cultures to determine their role(s) in autoimmune diseases and in degenerative diseases such as Alzheimer’s.

Acetylated LDL-SAP eliminates scavenger receptor-positive cells. This includes the macrophage and its relative, the microglia. All other cells are left untouched. Not suitable for retrograde transport.

To view protocol(s) for this and other products please visit:

View Acetylated LDL-SAP Data Sheet
View Saporin Data Sheet

View Related Acetylated LDL-SAP References
View Related Saporin References

You may also like…