Mab-ZAP uses your primary mouse monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This secondary conjugate uses the secondary antibody (affinity-purified goat anti-mouse IgG) to “piggyback” onto YOUR mouse primary antibody. Mab-ZAP can be utilized for screening mouse IgG antibodies for internalization and/or their suitability to make potent immunotoxins.
Mab-ZAP uses your mouse primary antibody to target and eliminate cells. This secondary conjugate is used to evaluate the potential of a primary antibody to internalize.
Three sizes are available; each kit includes assay reagents and the following aliquots of Mab-ZAP and control:
KIT-04-Z (tests 1 ab) includes 25 mcg each of Mab-ZAP and Control Goat-IgG-SAP
KIT-04-Z4 (tests 4 abs) includes 100 mcg each of Mab-ZAP and Control Goat-IgG-SAP
KIT-04-Z10 (tests 10 abs) includes 250 mcg each of Mab-ZAP and Control Goat-IgG-SAP