OX7-SAP [IT-02]

a tool for eliminating cells that express Thy-1.1 in rat, mouse, rabbit or guinea pig; targeted via the antibody to CD90 (OX7), eliminated via saporin

SKU: IT-02 Category: Product Size: 25 ug, 100 ug, 250 ug, 1 mg | Antibody Type: Monoclonal | Host: mouse | Reactivity: guinea pig, Mouse, rabbit, rat | Conjugate: saporin | Usage: eliminates cells |

OX7, also known as Thy-1, Thy 1.1 or CD90, is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, T lymphocytes (mouse), immature B cells (rat) and connective tissues. It is involved in regulation of adhesion and signal transduction by T cells. It may contribute to inhibition of proliferation differentiation of hematopoietic stem cells and neuron memory formation in the CNS. Administration of OX7-SAP results in elimination of Thy-1.1-positive cells in rat, mouse, rabbit, or guinea pig. Permanent and selective removal of Thy-1.1 positive cells makes an important animal model for the study of neurotransmitter receptors, neuroanatomy, neural response to injury, and inducible immune suppression. This makes OX7-SAP an excellent tool for specific targeting of neuronal projections through suicide transport.

OX7-SAP specifically eliminates cells that express Thy-1.1. All other cells are left untouched.

To view protocol(s) for this and other products please visit: www.ATSbio.com/support/protocols

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