Dopamine Transporter Rat Monoclonal (DAT-NT), Alexa488 labeled [FL-N18]


SKU: FL-N18 Category: Antibody Type: Monoclonal | Host: Rat | Reactivity: Human, rat | Conjugate: Alexa488 | Usage: immunoblotting, immunocytochemistry, immunohistochemistry |

The dopamine transporter (DAT) is a sodium-dependent reuptake carrier that is suspected to play a role in such neurologic and psychiatric disorders as Parkinson’s disease, Tourette’s disease, schizophrenia, and addiction. It is a12-transmembrane domain transporter with the N- and C- terminus regions located within the cytoplasm.

This antibody recognizes the N-terminus of the dopamine transporter (DAT-NT) in rat and human. It was produced in rat by immunization with a GST-DAT-NT fusion protein, then construction of a hybridoma with the murine nonsecreting myeloma cell line Sp2/0. The N-terminus, consisting of amino acids 1-66, was used to construct the fusion protein. It has been conjugated to the fluorescent dye Alexa488.

Applications include immunocytochemistry, immunohistochemistry, and immunoblotting.

To view protocol(s) for this and other products please visit:

View Data Sheet