OX7, also known as Thy-1, Thy 1.1 or CD90, is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, T lymphocytes (mouse), immature B cells (rat) and connective tissues. It is involved in regulation of adhesion and signal transduction by T cells. It may contribute to inhibition of proliferation differentiation of hematopoietic stem cells and neuron memory formation in the CNS.
This antibody recognizes cells that express Thy-1.1 in rat, mouse, rabbit or guinea pig. Note: Antibody reactivity and working conditions may vary between species. Anti-OX7 was created as a mouse monoclonal generated to rat Thy-1.1 (CD90). It has been conjugated to biotin via an amide bond. The antibody is routinely tested by flow cytometry.
Applications include immunohistochemistry, flow cytometry, radioimmunoassay, and immunoblotting. Causes glomerulosclerosis when injected intravenously.
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