Anti-PD-L1-SAP [BETA-014]

$50.00

anti-human PD-L1-saporin

SKU: BETA-014 Categories: , Product Size: 25 ug | Antibody Type: Polyclonal | Host: Rabbit | Reactivity: Human | Conjugate: streptavidin-saporin | Usage: eliminates cells |

Description

PD-L1, Programmed death-ligand 1, also known as B7-H1 and CD274, is a cell surface glycoprotein and a member of the B7 family of co-stimulatory molecules. CD274 isåÊexpressed constitutively on macrophages and dendritic cells, and is induced on activated T-cells, B-cells, endothelial cells and epithelial cells inåÊresponse to interferons. PD-L1 has dual function: inhibition of activated effector T cells and co-stimulation of naÌøve T cells. PD-L1 has also been shown to beåÊupregulated in cancer cells in order to invade the host immune system. Anti-PD-L1-SAP could be used as an effective tool to study cancer and the immuneåÊsystem.åÊ

This product is being offered as part of our Beta Testing program. It has saporin activity confirmed, peptide sequences published/confirmed, and/or antibody binding specificity published/confirmed. It has not been characterized or reported in scientific literature. The researcher who first publishes data* will receive a $500 credit for use on ATS products.

*Data subject to review by the scientific team at ATS. See complete details here.

Anti-PD-L1-SAP eliminates cells expressing human PD-L1 (CD274, B7-H1).

This product is being offered as part of our Beta Testing program. It has saporin activity confirmed, peptide sequences published/confirmed, and/or antibody binding specificity published/confirmed. It has not been characterized or reported in scientific literature. The researcher who first publishes data* will receive a $500 credit for use on ATS products.

*Data subject to review by the scientific team at ATS. See complete details here.

View Data Sheet

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