Cover Article: CBF Lesioning in Rabbits

Contributed by Dr. Thomas Beach, Sun Health Research Institute, Sun City, AZ Our hypothesis, developed through our own human and animal studies1-6 and the cell culture work of others (beginning with Nitsch7), is that the normal, age-related loss of cortical cholinergic innervation leads to Aβ deposition and Alzheimer’s disease. To test this hypothesis, we have been […]

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SP-SAP as Chronic Pain Therapeutic

ADVANCED TARGETING SYSTEMS ANNOUNCES ITS MOLECULAR NEUROSURGERY TECHNOLOGY OPENS DOOR TO PERMANENT RELIEF FOR CHRONIC PAIN SAN DIEGO, CA, NOVEMBER 18, 1999— Chronic, intractable pain afflicts millions of Americans. Pioneering new technology, called molecular neurosurgery and developed by Advanced Targeting Systems, a San Diego-based company, provides the springboard for a one-time injection of a targeted […]

SFN Poster of the Year 1999

Awarded by ATS at Society for Neuroscience (SFN) Miami, Florida • October 23-28, 1999 474.6 Abolition of cyanide-induced sympathoexcitation by selective lesion of bulbospinal catecholaminergic neurons. A.M. SCHREIHOFER* and P.G. GUYENET Univ. of Virginia. Cardiovascular regulation: central control III (POSTER) The rostral ventrolateral medulla (RVLM) contains BS C1 adrenergic cells and non-CA neurons whose relative […]

Abstracts from Society for Neuroscience (SFN) Symposium October 23-28, 1999 – Miami, Florida

271.1 Inhibition of mustard oil-induced thermal hyperalgesia in an operant escape task by substance P-saporin. R.G. WILEY*, D.A. LAPPI and C.J. VIERCK Univ. of Florida Brain Inst. and Adv. Targeting Systems, San Diego. Pain modulation: anatomy and physiology–substance P and NK-1 (POSTER) 272.8 Depletion of IB4-binding sensory neurons results in elevated nociceptive thresholds. L. VULCHANOVA*, […]

Society for Neuroscience (SFN) Symposium October 23-28, 1999 – Miami, Florida

Symposium:  “Exciting New Advances in Pain Research and Treatment Using Receptor Internalization Technologies” D.A. Thomas, NIDA-NIH (co-chair); R.G. Wiley, Vanderbilt University; W.J. Martin, UCSF; M.J. Iadorola, NIDCR-NIH; P. Mantyh, University of Minnesota; R.M. Caudle, University of Florida (co-chair)  A press conference was held prior to the Thursday, Oct. 28 symposium. Carl Hall, journalist for the […]